| Gene Symbol |
TXLNG
|
| Entrez Gene |
55787
|
| Alt Symbol |
CXorf15, ELRG, FIAT, LSR5, TXLNGX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
taxilin gamma
|
| Other Description |
environmental LPS-responding|environmental lipopolysaccharide-responding gene protein|factor inhibiting ATF4-mediated transcription|factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription|gamma-taxilin|lipopolysaccharide specific response-5 protein|lipopolysaccharide-specific response protein 5
|
| Swissprots |
Q5JNZ7 Q9NUQ3 Q2KQ75 Q9P0X1
|
| Accessions |
EAW98918 Q9NUQ3 AA731379 AF143740 AAF70546 AK002071 BAA92068 AK090800 AK123142 AW197225 AY739713 AAW65982 BC101572 AAI01573 BC101576 AAI01577 DA516680 DB098819 U56251 XM_005274558 XP_005274615 XM_011545543 XP_011543845 NM_001168683 NP_001162154 NM_018360 NP_060830
|
| Function |
May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression. {ECO:0000269|PubMed:15911876, ECO:0000269|PubMed:18068885}.
|
| Subcellular Location |
Nucleus membrane {ECO:0000269|PubMed:15911876}. Cytoplasm, cytosol {ECO:0000250}.
|
| Tissue Specificity |
Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:15184072}.
|