Gene Symbol | TXLNG |
---|---|
Entrez Gene | 55787 |
Alt Symbol | CXorf15, ELRG, FIAT, LSR5, TXLNGX |
Species | Human |
Gene Type | protein-coding |
Description | taxilin gamma |
Other Description | environmental LPS-responding|environmental lipopolysaccharide-responding gene protein|factor inhibiting ATF4-mediated transcription|factor inhibiting activating transcription factor 4 (ATF4)-mediated transcription|gamma-taxilin|lipopolysaccharide specific response-5 protein|lipopolysaccharide-specific response protein 5 |
Swissprots | Q5JNZ7 Q9NUQ3 Q2KQ75 Q9P0X1 |
Accessions | EAW98918 Q9NUQ3 AA731379 AF143740 AAF70546 AK002071 BAA92068 AK090800 AK123142 AW197225 AY739713 AAW65982 BC101572 AAI01573 BC101576 AAI01577 DA516680 DB098819 U56251 XM_005274558 XP_005274615 XM_011545543 XP_011543845 NM_001168683 NP_001162154 NM_018360 NP_060830 |
Function | May be involved in intracellular vesicle traffic. Inhibits ATF4-mediated transcription, possibly by dimerizing with ATF4 to form inactive dimers that cannot bind DNA. May be involved in regulating bone mass density through an ATF4-dependent pathway. May be involved in cell cycle progression. {ECO:0000269|PubMed:15911876, ECO:0000269|PubMed:18068885}. |
Subcellular Location | Nucleus membrane {ECO:0000269|PubMed:15911876}. Cytoplasm, cytosol {ECO:0000250}. |
Tissue Specificity | Ubiquitously expressed. Expressed at high level in heart and skeletal muscle. Expressed in brain, placenta, lung, liver, kidney and pancreas. {ECO:0000269|PubMed:15184072}. |
γ-taxilin CRISPR/Cas9 KO Plasmid (h) - sc-410032 from Santa Cruz Biotechnology
|
||||||||
γ-taxilin HDR Plasmid (h) - sc-410032-HDR from Santa Cruz Biotechnology
|
||||||||
γ-taxilin Double Nickase Plasmid (h) - sc-410032-NIC from Santa Cruz Biotechnology
|
||||||||
γ-taxilin Double Nickase Plasmid (h2) - sc-410032-NIC-2 from Santa Cruz Biotechnology
|
||||||||
γ-taxilin CRISPR Activation Plasmid (h) - sc-410032-ACT from Santa Cruz Biotechnology
|
||||||||
γ-taxilin CRISPR Activation Plasmid (h2) - sc-410032-ACT-2 from Santa Cruz Biotechnology
|
||||||||
γ-taxilin Lentiviral Activation Particles (h) - sc-410032-LAC from Santa Cruz Biotechnology
|
||||||||
γ-taxilin Lentiviral Activation Particles (h2) - sc-410032-LAC-2 from Santa Cruz Biotechnology
|
||||||||
γ-taxilin siRNA (h) - sc-61650 from Santa Cruz Biotechnology
|
||||||||
γ-taxilin shRNA Plasmid (h) - sc-61650-SH from Santa Cruz Biotechnology
|
||||||||
γ-taxilin shRNA (h) Lentiviral Particles - sc-61650-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU022521 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22299 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22299 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02932 from Sigma-Aldrich
|
||||||||
TXLNG siRNA (Human) - CRJ0921 from Cohesion Biosciences
|
||||||||
TXLNG - MBS8222929 from MyBioSource
|
||||||||
shRNA set against Human TXLNG (NM_018360.2) - SHH438144 from Creative biogene
|
||||||||
TXLNG shRNA Plasmid (Human) - CHJ0921 from Cohesion Biosciences
|
||||||||
TXLNG miRNA 3'UTR clone - MiUTR4H-TG09533 from Creative biogene
|