| Gene Symbol |
DOHH
|
| Entrez Gene |
83475
|
| Alt Symbol |
HLRC1, hDOHH
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
deoxyhypusine hydroxylase/monooxygenase
|
| Other Description |
HEAT-like (PBS lyase) repeat containing 1|HEAT-like repeat-containing protein 1|deoxyhypusine dioxygenase|deoxyhypusine hydroxylase|deoxyhypusine monooxygenase
|
| Swissprots |
Q9BU89 O75265
|
| Accessions |
AAC33193 EAW69316 EAW69317 Q9BU89 AW195139 BC002817 AAH02817 BC009863 AAH09863 BG491509 BU624567 XM_011528340 XP_011526642 XM_011528341 XP_011526643 NM_001145165 NP_001138637 NM_031304 NP_112594
|
| Function |
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor. {ECO:0000255|HAMAP-Rule:MF_03101, ECO:0000269|PubMed:16371467, ECO:0000269|PubMed:19706422}.
|