Gene Symbol | DOHH |
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Entrez Gene | 83475 |
Alt Symbol | HLRC1, hDOHH |
Species | Human |
Gene Type | protein-coding |
Description | deoxyhypusine hydroxylase/monooxygenase |
Other Description | HEAT-like (PBS lyase) repeat containing 1|HEAT-like repeat-containing protein 1|deoxyhypusine dioxygenase|deoxyhypusine hydroxylase|deoxyhypusine monooxygenase |
Swissprots | Q9BU89 O75265 |
Accessions | AAC33193 EAW69316 EAW69317 Q9BU89 AW195139 BC002817 AAH02817 BC009863 AAH09863 BG491509 BU624567 XM_011528340 XP_011526642 XM_011528341 XP_011526643 NM_001145165 NP_001138637 NM_031304 NP_112594 |
Function | Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)- L-lysine intermediate to form hypusine, an essential post- translational modification only found in mature eIF-5A factor. {ECO:0000255|HAMAP-Rule:MF_03101, ECO:0000269|PubMed:16371467, ECO:0000269|PubMed:19706422}. |
DOHH CRISPR/Cas9 KO Plasmid (h) - sc-404524 from Santa Cruz Biotechnology
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DOHH HDR Plasmid (h) - sc-404524-HDR from Santa Cruz Biotechnology
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DOHH Double Nickase Plasmid (h) - sc-404524-NIC from Santa Cruz Biotechnology
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DOHH Double Nickase Plasmid (h2) - sc-404524-NIC-2 from Santa Cruz Biotechnology
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DOHH CRISPR Activation Plasmid (h) - sc-404524-ACT from Santa Cruz Biotechnology
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DOHH CRISPR Activation Plasmid (h2) - sc-404524-ACT-2 from Santa Cruz Biotechnology
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DOHH Lentiviral Activation Particles (h) - sc-404524-LAC from Santa Cruz Biotechnology
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DOHH Lentiviral Activation Particles (h2) - sc-404524-LAC-2 from Santa Cruz Biotechnology
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DOHH siRNA (h) - sc-62222 from Santa Cruz Biotechnology
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DOHH shRNA Plasmid (h) - sc-62222-SH from Santa Cruz Biotechnology
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DOHH shRNA (h) Lentiviral Particles - sc-62222-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN7426 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7426 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05834 from Sigma-Aldrich
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DOHH siRNA (Human) - CRJ3113 from Cohesion Biosciences
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DOHH - MBS8222103 from MyBioSource
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DOHH shRNA Plasmid (Human) - CHJ3113 from Cohesion Biosciences
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DOHH miRNA 3'UTR clone - MiUTR3H-11757 from Creative biogene
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DOHH miRNA 3'UTR clone - MiUTR3H-11758 from Creative biogene
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