Gene Symbol | NME8 |
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Entrez Gene | 51314 |
Alt Symbol | CILD6, NM23-H8, SPTRX2, TXNDC3, sptrx-2 |
Species | Human |
Gene Type | protein-coding |
Description | NME/NM23 family member 8 |
Other Description | sperm-specific thioredoxin 2|spermatid-specific thioredoxin-2|thioredoxin domain containing 3 (spermatozoa)|thioredoxin domain-containing protein 3 |
Swissprots | Q8N427 Q9NZH1 |
Accessions | EAW94083 EAW94084 Q8N427 AF202051 AAF20909 AF305596 AAN04258 AK313599 BAG36365 BC036816 AAH36816 JF432242 ADZ15459 NM_016616 NP_057700 |
Function | Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:11737268}. |
Tissue Specificity | Testis-specific. Expressed only in primary spermatocytes and round spermatids. {ECO:0000269|PubMed:11737268}. |
Sptrx-2 (C-13) - sc-160840 from Santa Cruz Biotechnology
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Sptrx-2 (G-15) - sc-160841 from Santa Cruz Biotechnology
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Sptrx-2 (N-14) - sc-160842 from Santa Cruz Biotechnology
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Sptrx-2 (KK-M5) - sc-135567 from Santa Cruz Biotechnology
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Anti-TXNDC3 antibody - ab77658 from Abcam
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Anti-TXNDC3 antibody - ab96396 from Abcam
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Anti-TXNDC3 antibody - ab67836 from Abcam
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Anti-TXNDC3 Antibody (Internal) - LS-C112769 from LifeSpan Bioscience
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Anti-TXNDC3 Antibody (aa270-550) - LS-C186216 from LifeSpan Bioscience
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TXNDC3 Antibody - NBP1-85616 from Novus Biologicals
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TXNDC3 Antibody - H00051314-B01 from Novus Biologicals
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TXNDC3 Antibody - H00051314-B01P from Novus Biologicals
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TXNDC3 Antibody - H00051314-D01P from Novus Biologicals
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TXNDC3 Antibody - NBP1-33142 from Novus Biologicals
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TXNDC3 Antibody (1G5) - H00051314-M01 from Novus Biologicals
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TXNDC3 Antibody - NBP1-37001 from Novus Biologicals
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Monoclonal Anti-TXNDC3 antibody produced in mouse - SAB1400549 from Sigma-Aldrich
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Anti-TXNDC3 antibody produced in rabbit - SAB1408680 from Sigma-Aldrich
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Anti-TXNDC3 antibody produced in mouse - SAB1400548 from Sigma-Aldrich
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Anti-NME8 antibody produced in rabbit - HPA019259 from Sigma-Aldrich
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TXNDC3-Antibody-monoclonal-M01 - AT4416a from Abgent, a WuXi AppTec company
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TXNDC3-Antibody-internal-region - AF2762a from Abgent, a WuXi AppTec company
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TXNDC3 antibody - orb69882 from Biorbyt
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TXNDC3 Antibody (OAEB00263) - OAEB00263 from Aviva Systems Biology
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TXNDC3 antibody - 70R-21076 from Fitzgerald
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