KLK14

Gene Symbol	KLK14
Entrez Gene	43847
Alt Symbol	KLK-L6
Species	Human
Gene Type	protein-coding
Description	kallikrein-related peptidase 14
Other Description	hK14|kallikrein 14|kallikrein-14|kallikrein-like protein 6
Swissprots	Q6B089 A7UNK5 Q9P0G3 Q1RMZ2
Accessions	AAD50773 AAG23260 AAK48523 ABU63131 EAW71982 EAW71983 Q9P0G3 AF283670 AAK48524 BC074904 AAH74904 BC074905 AAH74905 BC114614 AAI14615 XM_011526984 XP_011525286 XM_011526985 XP_011525287 NM_022046 NP_071329
Function	Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression including growth, invasion and angiogenesis. {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:16885167, ECO:0000269|PubMed:17158887, ECO:0000269|PubMed:17625593, ECO:0000269|PubMed:18056261, ECO:0000269|PubMed:18482984}.
Subcellular Location	Secreted, extracellular space {ECO:0000269|PubMed:15654974, ECO:0000269|PubMed:16456535, ECO:0000269|PubMed:17110383}.
Tissue Specificity	Highly expressed in CNS, bone marrow and fetal liver. Also expressed in breast, thyroid, kidney, colon, pancreas, spleen, prostate, uterus, small intestine, placenta and skeletal muscle. Among 40 tissues tested, the highest expression is detected in skin followed by breast and prostate (at protein level). Expressed in stratum corneum by sweat ducts and sweat glands and detected in sweat (at protein level). {ECO:0000269|PubMed:10969073, ECO:0000269|PubMed:11309303, ECO:0000269|PubMed:11352573, ECO:0000269|PubMed:16456535, ECO:0000269|PubMed:16800737, ECO:0000269|PubMed:17110383}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

KLK14 (P-14) - sc-20393 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Kallikrein 14 antibody - ab203226 from Abcam Prices $359.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Kallikrein 14 antibody - ab88674 from Abcam Prices $370.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-Kallikrein 14 antibody - ab167234 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-Kallikrein 14 antibody [EPR7209] - ab128957 from Abcam Prices $313.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7209

Anti-Kallikrein 14 antibody - Catalytic domain - ab40960 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Kallikrein 14 antibody - Kallikrein loop - ab28568 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa239-251) - LS-C53390 from LifeSpan Bioscience Prices $445.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa239-251) - LS-C83560 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa239-251) - LS-C40672 from LifeSpan Bioscience Prices $275.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (C-Terminus) - LS-C137170 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, APC) - LS-C215471 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, AP) - LS-C215472 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, Biotin) - LS-C215473 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, FITC) - LS-C215474 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, Azide-free, HRP) - LS-C215475 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody - LS-C136903 from LifeSpan Bioscience Prices $255.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44, PE) - LS-C215476 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (C-Terminus, clone EPR7209) - LS-C152432 from LifeSpan Bioscience Prices $395.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR7209

Anti-KLK14 / Kallikrein 14 Antibody (aa152-252) - LS-C308578 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa14-44) - LS-C329736 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa239-251) - LS-C2798 from LifeSpan Bioscience Prices $335.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-KLK14 / Kallikrein 14 Antibody (aa15-44) - LS-C165582 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Kallikrein 14 Antibody - AF2626 from Novus Biologicals Prices $99.00, $359.00 Sizes 25 µg, 100 µg Host Goat Clonality Polyclonal

Kallikrein 14 Antibody (337903) - MAB2626 from Novus Biologicals Prices $99.00, $249.00 Sizes 25 µg, 100 µg Host Mouse Clonality Monoclonal Clone 337903

Search more