EIF3D

Gene Symbol EIF3D
Entrez Gene 8664
Alt Symbol EIF3S7, eIF3-p66, eIF3-zeta
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 3, subunit D
Other Description eIF3 p66|eukaryotic translation initiation factor 3 subunit D|eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa|translation initiation factor eIF3 p66 subunit
Swissprots B2R7D4 Q3MJD9 B4DTF8 A8MWD3 O15371 Q5M9Q6 B4DVY1
Accessions EAW60109 EAW60110 O15371 AK300199 BAG61970 AK301284 BAG62843 AK303884 BAG64820 AK312939 BAG35781 AW575097 BC000328 AAH00328 BC000469 AAH00469 BC014912 AAH14912 BC080515 AAH80515 BC093100 AAH93100 BC093686 AAH93686 BC101477 AAI01478 BG718662 BT007381 AAP36045 CR456489 CAG30375 CU013049 CAK54480 CU013337 CAK54779 DQ891129 ABM82055 DQ894308 ABM85234 U54558 AAD03466 XM_011530479 XP_011528781 XR_937944 NM_003753 NP_003744
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Subcellular Location Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03003}.
Top Pathways RNA transport

eIF3ζ (H-300) - sc-28856 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
eIF3ζ (H-300): sc-28856. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

eIF3ζ (P-20) - sc-31896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
eIF3ζ (P-20): sc-31896. Western blot analysis of eIF3ζ expression in HeLa whole cell lysate.

eIF3ζ (Y-20) - sc-16372 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EIF3D antibody - ab155419 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EIF3D antibody (ab155419) at 1/1000 dilution + HeLa S3 whole cell lysate at 30 µg

Anti-EIF3D antibody - ab109990 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab109990 at 1/50 dilution staining EIF3D in paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-EIF3D antibody - ab124442 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-EIF3D antibody (ab124442) at 1/500 dilution + K562 cell lysate

Anti-EIF3D antibody - ab85951 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EIF3D antibody (ab85951) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-EIF3D antibody - ab128654 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-EIF3D antibody (ab128654) at 1 µg/ml + Rat Liver lysate at 10 µg

Anti-EIF3D Antibody (aa150-200) - LS-C125516 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF3D Antibody (aa150-200) - LS-C288539 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF3D Antibody (N-Terminus) - LS-C151482 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF3D antibody Western Blot of Rat liver.

Anti-EIF3D Antibody (aa124-173) - LS-C146008 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF3D antibody LS-C146008 Western blot of HT1080 Cell lysate. Antibody concentration 1 ug/ml.

Anti-EIF3D Antibody (aa500-550) - LS-C148514 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of eIF3D in human brain lysate in the 1) absence and 2) presence of immunizing peptide, 3) mouse brain and 4) rat brain lysate using LS-C148514 at 0.01 ug/ml, 0.01 ug/ml, 0.005 ug/ml and 0.01 ug/ml, respectively.

Anti-EIF3D Antibody (aa200-250) - LS-C288540 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human eIF3D/EIF3S7 by Western Blot. Samples: Whole cell lysate from HeLa (5, 15 and 50 ug for WB) and 293T (T; 50 ug) cells. Antibodies: Affinity purified rabbit anti-eIF3D/EIF3S7 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Anti-EIF3D Antibody (clone 14D6) - LS-C340457 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 14D6
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-EIF3D mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)(1:150).

Anti-EIF3D Antibody (Arg135) - LS-C177835 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of eIF3 (R135) pAb in paraffin-embedded human breast carcinoma tissue.

Anti-EIF3D Antibody - LS-C334408 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of Mouse brain cell lines, using EIF3D antibody.

Anti-EIF3D Antibody (aa101-150) IHC-plus™ - LS-B5687 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EIF3D antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5687 concentration 10 ug/ml.

EIF3D Antibody - NBP2-24468 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

EIF3D Antibody - NBP1-51365 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EIF3D Antibody [NBP1-51365] - Extracts from 3T3 cells.

EIF3D Antibody - NBP2-39069 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EIF3D Antibody [NBP2-39069] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

EIF3D Antibody - NBP2-38990 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

EIF3D Antibody - NB100-93299 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: EIF3D Antibody [NB100-93299] - Detection of Human eIF3D/EIF3S7 on HeLa whole cell lysate. eIF3D/EIF3S7 was not efficiently immunoprecipitated by rabbit anti-eIF3D/EIF3S7 antibody NB100-93300.

EIF3D Antibody - NBP1-68502 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: EIF3D Antibody [NBP1-68502] - Analysis of extracts from NIH-3T3 cells, using EIF3D Antibody. The lane on the right is treated with the synthesized peptide.

Anti-EIF3D (46-60) antibody produced in rabbit - SAB1100682 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-EIF3D (46-60) : <B>Cat. No. SAB1100682</B>: Immunofluorescence of HUVEC cells using EIF3D (46-60) , Cat. No. SAB1100682 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com
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