Gene Symbol |
RND2
|
Entrez Gene |
8153
|
Alt Symbol |
ARHN, RHO7, RhoN
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
Rho family GTPase 2
|
Other Description |
CTD-3199J23.4|GTP-binding protein Rho7|ras homolog gene family, member N|rho-related GTP-binding protein Rho7|rho-related GTP-binding protein RhoN
|
Swissprots |
O00734 A8K2D4 Q99535 Q5U0P6 O00690 P52198
|
Accessions |
AAC37595 EAW60919 EAW60920 P52198 AB209778 BAD93015 AF498968 AAM21115 AK096367 AK290199 BAF82888 BC018096 BC094842 AAH94842 BC104986 AAI04987 BC104990 AAI04991 BT019394 AAV38201 BU687800 DB502558 X95456 CAA64726 XM_011525316 XP_011523618 XM_011525317 XP_011523619 NM_005440 NP_005431
|
Function |
May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. {ECO:0000269|PubMed:12590651}.
|
Tissue Specificity |
Highly expressed in testis.
|