Gene Symbol | RND2 |
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Entrez Gene | 8153 |
Alt Symbol | ARHN, RHO7, RhoN |
Species | Human |
Gene Type | protein-coding |
Description | Rho family GTPase 2 |
Other Description | CTD-3199J23.4|GTP-binding protein Rho7|ras homolog gene family, member N|rho-related GTP-binding protein Rho7|rho-related GTP-binding protein RhoN |
Swissprots | O00734 A8K2D4 Q99535 Q5U0P6 O00690 P52198 |
Accessions | AAC37595 EAW60919 EAW60920 P52198 AB209778 BAD93015 AF498968 AAM21115 AK096367 AK290199 BAF82888 BC018096 BC094842 AAH94842 BC104986 AAI04987 BC104990 AAI04991 BT019394 AAV38201 BU687800 DB502558 X95456 CAA64726 XM_011525316 XP_011523618 XM_011525317 XP_011523619 NM_005440 NP_005431 |
Function | May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasmic vesicle, secretory vesicle, acrosome membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Note=Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome. {ECO:0000269|PubMed:12590651}. |
Tissue Specificity | Highly expressed in testis. |
Rho 7 CRISPR/Cas9 KO Plasmid (h) - sc-404094 from Santa Cruz Biotechnology
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Rho 7 HDR Plasmid (h) - sc-404094-HDR from Santa Cruz Biotechnology
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Rho 7 Double Nickase Plasmid (h) - sc-404094-NIC from Santa Cruz Biotechnology
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Rho 7 Double Nickase Plasmid (h2) - sc-404094-NIC-2 from Santa Cruz Biotechnology
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Rho 7 CRISPR Activation Plasmid (h) - sc-404094-ACT from Santa Cruz Biotechnology
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Rho 7 CRISPR Activation Plasmid (h2) - sc-404094-ACT-2 from Santa Cruz Biotechnology
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Rho 7 Lentiviral Activation Particles (h) - sc-404094-LAC from Santa Cruz Biotechnology
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Rho 7 Lentiviral Activation Particles (h2) - sc-404094-LAC-2 from Santa Cruz Biotechnology
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Rho 7 siRNA (h) - sc-41879 from Santa Cruz Biotechnology
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Rho 7 shRNA Plasmid (h) - sc-41879-SH from Santa Cruz Biotechnology
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Rho 7 shRNA (h) Lentiviral Particles - sc-41879-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU020631 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18360 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18360 from Sigma-Aldrich
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RND2 siRNA (Human) - CRH5381 from Cohesion Biosciences
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RND2 RNAi - H00008153-R01 from Novus Biologicals
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RND2 - MBS827632 from MyBioSource
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shRNA set against Human RND2 (NM_005440.4) - SHH396464 from Creative biogene
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shRNA set against Human RND2(NM_005440.4) - SHR184650 from Creative biogene
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Human RND2 siRNA - orb265883 from Biorbyt
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RND2 shRNA Plasmid (Human) - CHH5381 from Cohesion Biosciences
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RND2 miRNA 3'UTR clone - MiUTR1H-08866 from Creative biogene
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