| Gene Symbol |
ENTPD2
|
| Entrez Gene |
954
|
| Alt Symbol |
CD39L1, NTPDase-2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ectonucleoside triphosphate diphosphohydrolase 2
|
| Other Description |
CD39 antigen-like 1|NTPDase 2|ecto-ATP diphosphohydrolase 2|ecto-ATPDase 2|ecto-ATPase 2
|
| Swissprots |
Q5SPY7 Q9Y5L3 Q5SPY6 O15464
|
| Accessions |
EAW88336 EAW88337 Q9Y5L3 AF144748 AAD40239 BC011003 BC035738 AAH35738 BQ883059 CB045339 DQ892410 ABM83336 DQ895623 ABM86549 EF495152 ABP58644 U91510 AAB81013 XM_011519211 XP_011517513 XM_011519212 XP_011517514 NM_001246 NP_001237 NM_203468 NP_982293
|
| Function |
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP.
|
| Subcellular Location |
Isoform gamma: Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes.
|
| Top Pathways |
Purine metabolism
|
![Western Blot: ENTPD2 Overexpression Lysate (Adult Normal) [NBL1-10281] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ENTPD2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10010_ENTPD2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-10281-img0002.jpg)