| Gene Symbol |
GNGT2
|
| Entrez Gene |
2793
|
| Alt Symbol |
G-GAMMA-8, G-GAMMA-C, GNG8, GNG9, GNGT8
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
|
| Other Description |
G protein cone gamma 8 subunit|G-gamma-9|g gamma-C|gamma-T2 subunit|guanine nucleotide binding protein gamma 9|guanine nucleotide binding protein gamma transducing activity polypeptide 2|guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2
|
| Swissprots |
B2R746 D3DTW5 O14610
|
| Accessions |
AAB70039 EAW94688 EAW94689 O14610 AF365870 AAK53384 AF493876 AAM12590 AI857683 AK312839 BAG35693 BC008663 AAH08663 BM723861 BU742490 DA248836 HQ448708 ADQ33186 XM_006721819 XP_006721882 NM_001198754 NP_001185683 NM_001198755 NP_001185684 NM_001198756 NP_001185685 NM_031498 NP_113686
|
| Function |
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
|
| Tissue Specificity |
Retinal cones.
|
| Top Pathways |
Dopaminergic synapse, Morphine addiction, Glutamatergic synapse, PI3K-Akt signaling pathway, GABAergic synapse
|
![Western Blot: G gamma14 Overexpression Lysate (Adult Normal) [NBP2-06120] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for G gamma14.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7721_G%2520gamma14%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06120-img0001.jpg)