Gene Symbol | CYP2R1 |
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Entrez Gene | 120227 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 2, subfamily R, polypeptide 1 |
Other Description | cytochrome P450 2R1|cytochrome P450, family 2, R1|vitamin D 25-hydroxylase |
Swissprots | Q5RT65 Q6VVX0 Q2M3H3 |
Accessions | AAV65814 EAW68470 EAW68471 EAW68472 EAW68473 Q6VVX0 AK092584 AK312019 BAG34956 AW138676 AY323817 AAQ23114 BC052580 BC084557 BC104907 AAI04908 BC104909 AAI04910 BC111070 XM_005252788 XP_005252845 XM_005252789 XP_005252846 XM_005252791 XP_005252848 XM_006718142 XP_006718205 XM_011519894 XP_011518196 XM_011519895 XP_011518197 XM_011519896 XP_011518198 XM_011519897 XP_011518199 XM_011519898 XP_011518200 XR_242777 NM_024514 NP_078790 |
Function | Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). {ECO:0000269|PubMed:12867411, ECO:0000269|PubMed:15465040, ECO:0000269|PubMed:18511070}. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Top Pathways | Steroid biosynthesis |
CYP2R1 (C-15) - sc-48985 from Santa Cruz Biotechnology
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CYP2R1 (H-100) - sc-98919 from Santa Cruz Biotechnology
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CYP2R1 (T-12) - sc-48987 from Santa Cruz Biotechnology
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CYP2R1 (T-18) - sc-48988 from Santa Cruz Biotechnology
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Anti-CYP2R1 antibody - ab137634 from Abcam
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Anti-CYP2R1 antibody - ab80101 from Abcam
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Anti-CYP2R1 antibody - ab79924 from Abcam
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Anti-CYP2R1 antibody - ab136110 from Abcam
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Anti-CYP2R1 antibody - ab70514 from Abcam
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (aa230-279) - LS-C291858 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody - LS-C307848 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody - LS-C311069 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (C-Terminus) - LS-C201567 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (aa251-300) - LS-C119501 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (aa179-228) - LS-C135234 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (Internal) - LS-C99449 from LifeSpan Bioscience
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Anti-Cytochrome P450 2R1 / CYP2R1 Antibody (C-Terminus) - LS-C99448 from LifeSpan Bioscience
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CYP2R1 Antibody - NBP1-32883 from Novus Biologicals
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CYP2R1 Antibody - NBP2-13895 from Novus Biologicals
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CYP2R1 Antibody - H00120227-B01P from Novus Biologicals
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CYP2R1 Antibody - H00120227-D01P from Novus Biologicals
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CYP2R1 Antibody - H00120227-B01 from Novus Biologicals
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CYP2R1 Polyclonal Antibody - bs-3900R from Bioss
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Anti-CYP2R1 (center) antibody produced in rabbit - SAB1300955 from Sigma-Aldrich
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Anti-CYP2R1 antibody produced in rabbit - HPA042949 from Sigma-Aldrich
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