Gene Symbol |
CYP2R1
|
Entrez Gene |
120227
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cytochrome P450, family 2, subfamily R, polypeptide 1
|
Other Description |
cytochrome P450 2R1|cytochrome P450, family 2, R1|vitamin D 25-hydroxylase
|
Swissprots |
Q5RT65 Q6VVX0 Q2M3H3
|
Accessions |
AAV65814 EAW68470 EAW68471 EAW68472 EAW68473 Q6VVX0 AK092584 AK312019 BAG34956 AW138676 AY323817 AAQ23114 BC052580 BC084557 BC104907 AAI04908 BC104909 AAI04910 BC111070 XM_005252788 XP_005252845 XM_005252789 XP_005252846 XM_005252791 XP_005252848 XM_006718142 XP_006718205 XM_011519894 XP_011518196 XM_011519895 XP_011518197 XM_011519896 XP_011518198 XM_011519897 XP_011518199 XM_011519898 XP_011518200 XR_242777 NM_024514 NP_078790
|
Function |
Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). {ECO:0000269|PubMed:12867411, ECO:0000269|PubMed:15465040, ECO:0000269|PubMed:18511070}.
|
Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
Top Pathways |
Steroid biosynthesis
|