| Gene Symbol |
ASB9
|
| Entrez Gene |
140462
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ankyrin repeat and SOCS box containing 9
|
| Other Description |
ASB-9|ankyrin repeat and SOCS box protein 9|ankyrin repeat and SOCS box-containing 9|ankyrin repeat and suppressor of cytokine signaling box protein 9
|
| Swissprots |
Q9BVF5 Q96DX5 A8K8A5 Q9NWS5 Q9Y4T3
|
| Accessions |
EAW98870 EAW98871 EAW98872 EAW98873 EAW98874 EAW98875 EAW98876 Q96DX5 AK000643 BAA91302 AK292270 BAF84959 AL080091 CAB45706 AY337578 AAQ17469 BC001244 AAH01244 BC013172 AAH13172 DA943920 XM_005274446 XP_005274503 XM_011545458 XP_011543760 XM_011545459 XP_011543761 XM_011545460 XP_011543762 NM_001031739 NP_001026909 NM_001168530 NP_001162002 NM_001168531 NP_001162003 NM_024087 NP_076992
|
| Function |
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. {ECO:0000269|PubMed:22418839}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:20302626}.
|
| Tissue Specificity |
Predominantly expressed in testis, kidney, and liver. {ECO:0000269|PubMed:20302626}.
|
![Western Blot: ASB9 Overexpression Lysate (Adult Normal) [NBL1-07756] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ASB9.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14098_ASB9%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-07756-img0002.jpg)