Gene Symbol | ASB9 |
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Entrez Gene | 140462 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | ankyrin repeat and SOCS box containing 9 |
Other Description | ASB-9|ankyrin repeat and SOCS box protein 9|ankyrin repeat and SOCS box-containing 9|ankyrin repeat and suppressor of cytokine signaling box protein 9 |
Swissprots | Q9BVF5 Q96DX5 A8K8A5 Q9NWS5 Q9Y4T3 |
Accessions | EAW98870 EAW98871 EAW98872 EAW98873 EAW98874 EAW98875 EAW98876 Q96DX5 AK000643 BAA91302 AK292270 BAF84959 AL080091 CAB45706 AY337578 AAQ17469 BC001244 AAH01244 BC013172 AAH13172 DA943920 XM_005274446 XP_005274503 XM_011545458 XP_011543760 XM_011545459 XP_011543761 XM_011545460 XP_011543762 NM_001031739 NP_001026909 NM_001168530 NP_001162002 NM_001168531 NP_001162003 NM_024087 NP_076992 |
Function | Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A. {ECO:0000269|PubMed:22418839}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:20302626}. |
Tissue Specificity | Predominantly expressed in testis, kidney, and liver. {ECO:0000269|PubMed:20302626}. |
ASB-9 CRISPR/Cas9 KO Plasmid (h) - sc-417425 from Santa Cruz Biotechnology
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ASB-9 HDR Plasmid (h) - sc-417425-HDR from Santa Cruz Biotechnology
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ASB-9 Double Nickase Plasmid (h) - sc-417425-NIC from Santa Cruz Biotechnology
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ASB-9 Double Nickase Plasmid (h2) - sc-417425-NIC-2 from Santa Cruz Biotechnology
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ASB-9 CRISPR Activation Plasmid (h) - sc-417425-ACT from Santa Cruz Biotechnology
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ASB-9 CRISPR Activation Plasmid (h2) - sc-417425-ACT-2 from Santa Cruz Biotechnology
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ASB-9 Lentiviral Activation Particles (h) - sc-417425-LAC from Santa Cruz Biotechnology
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ASB-9 Lentiviral Activation Particles (h2) - sc-417425-LAC-2 from Santa Cruz Biotechnology
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ASB-9 siRNA (h) - sc-91095 from Santa Cruz Biotechnology
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ASB-9 shRNA Plasmid (h) - sc-91095-SH from Santa Cruz Biotechnology
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ASB-9 shRNA (h) Lentiviral Particles - sc-91095-V from Santa Cruz Biotechnology
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ASB9 RNAi - H00140462-R01 from Novus Biologicals
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ASB9 RNAi - H00140462-R02 from Novus Biologicals
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MISSION® esiRNA - EHU025961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3583 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3583 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05233 from Sigma-Aldrich
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ASB9 siRNA (Human) - CRJ5281 from Cohesion Biosciences
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ASB9 - MBS8226898 from MyBioSource
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shRNA set against Human ASB9 (NM_024087.2) - SHH241330 from Creative biogene
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Human ASB9 siRNA - orb275782 from Biorbyt
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ASB9 shRNA Plasmid (Human) - CHJ5281 from Cohesion Biosciences
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