Gene Symbol | SAP30 |
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Entrez Gene | 8819 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | Sin3A-associated protein, 30kDa |
Other Description | 30 kDa Sin3-associated polypeptide|Sin3 corepressor complex subunit SAP30|Sin3-associated polypeptide, 30kDa|histone deacetylase complex subunit SAP30|sin3-associated polypeptide p30|sin3-associated polypeptide, 30 kDa |
Swissprots | D3DP38 O75446 |
Accessions | EAX04755 EAX04756 O75446 AF055993 AAC33316 AW236579 BC016757 AAH16757 DQ892828 ABM83754 NM_003864 NP_003855 |
Function | Involved in the functional recruitment of the Sin3- histone deacetylase complex (HDAC) to a specific subset of N-CoR corepressor complexes. Capable of transcription repression by N- CoR. Active in deacetylating core histone octamers (when in a complex) but inactive in deacetylating nucleosomal histones. {ECO:0000250|UniProtKB:O88574, ECO:0000269|PubMed:9651585}. |
Subcellular Location | Nucleus. |
Tissue Specificity | Expressed in all tissues tested with highest levels in pancreas, ovary, PBL, spleen and thymus; lowest levels in brain, placenta, lung and kidney. {ECO:0000269|PubMed:9702189}. |
SAP 30 CRISPR/Cas9 KO Plasmid (h) - sc-404691 from Santa Cruz Biotechnology
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SAP 30 HDR Plasmid (h) - sc-404691-HDR from Santa Cruz Biotechnology
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SAP 30 Double Nickase Plasmid (h) - sc-404691-NIC from Santa Cruz Biotechnology
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SAP 30 Double Nickase Plasmid (h2) - sc-404691-NIC-2 from Santa Cruz Biotechnology
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SAP 30 CRISPR Activation Plasmid (h) - sc-404691-ACT from Santa Cruz Biotechnology
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SAP 30 CRISPR Activation Plasmid (h2) - sc-404691-ACT-2 from Santa Cruz Biotechnology
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SAP 30 Lentiviral Activation Particles (h) - sc-404691-LAC from Santa Cruz Biotechnology
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SAP 30 Lentiviral Activation Particles (h2) - sc-404691-LAC-2 from Santa Cruz Biotechnology
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SAP 30 siRNA (h) - sc-44086 from Santa Cruz Biotechnology
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SAP 30 shRNA Plasmid (h) - sc-44086-SH from Santa Cruz Biotechnology
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SAP 30 shRNA (h) Lentiviral Particles - sc-44086-V from Santa Cruz Biotechnology
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SAP30 RNAi - H00008819-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN18845 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18845 from Sigma-Aldrich
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SAP30 siRNA (Human) - CRH5817 from Cohesion Biosciences
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SAP30 - MBS8220759 from MyBioSource
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shRNA set against Human SAP30(NM_003864.3) - SHR204738 from Creative biogene
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Human SAP30 siRNA - orb266319 from Biorbyt
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SAP30 shRNA Plasmid (Human) - CHH5817 from Cohesion Biosciences
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SAP30 miRNA 3'UTR clone - MiUTR1H-09135 from Creative biogene
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