Gene Symbol | GGPS1 |
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Entrez Gene | 9453 |
Alt Symbol | GGPPS, GGPPS1 |
Species | Human |
Gene Type | protein-coding |
Description | geranylgeranyl diphosphate synthase 1 |
Other Description | (2E,6E)-farnesyl diphosphate synthase|GGPP synthase|GGPPSase|dimethylallyltranstransferase|farnesyl diphosphate synthase|farnesyltranstransferase|geranylgeranyl pyrophosphate synthase|geranyltranstransferase |
Swissprots | Q6NW19 O95749 A8MVQ8 Q5T2C8 |
Accessions | EAW70016 EAW70017 EAW70018 EAW70019 EAW70020 O95749 AB016043 BAA76511 AB017971 BAA75909 AB019036 BAA77251 AF057698 AAG45581 AF125394 AAD43050 AI088775 AK025139 AK293278 BAH11480 BC005252 AAH05252 BC067768 AAH67768 BI462253 BI520491 BI963107 CB216084 DB473584 HQ448140 ADQ32621 NM_001037277 NP_001032354 NR_036605 NM_001037278 NM_004837 |
Function | Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Abundantly expressed in testis. Found in other tissues to a lower extent. |
Top Pathways | Terpenoid backbone biosynthesis |
GGPS1 CRISPR/Cas9 KO Plasmid (h) - sc-404003 from Santa Cruz Biotechnology
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GGPS1 HDR Plasmid (h) - sc-404003-HDR from Santa Cruz Biotechnology
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GGPS1 Double Nickase Plasmid (h) - sc-404003-NIC from Santa Cruz Biotechnology
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GGPS1 Double Nickase Plasmid (h2) - sc-404003-NIC-2 from Santa Cruz Biotechnology
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GGPS1 CRISPR Activation Plasmid (h) - sc-404003-ACT from Santa Cruz Biotechnology
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GGPS1 CRISPR Activation Plasmid (h2) - sc-404003-ACT-2 from Santa Cruz Biotechnology
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GGPS1 Lentiviral Activation Particles (h) - sc-404003-LAC from Santa Cruz Biotechnology
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GGPS1 Lentiviral Activation Particles (h2) - sc-404003-LAC-2 from Santa Cruz Biotechnology
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GGPS1 siRNA (h) - sc-88605 from Santa Cruz Biotechnology
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GGPS1 shRNA Plasmid (h) - sc-88605-SH from Santa Cruz Biotechnology
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GGPS1 shRNA (h) Lentiviral Particles - sc-88605-V from Santa Cruz Biotechnology
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GGPS1 RNAi - H00009453-R01 from Novus Biologicals
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GGPS1 RNAi - H00009453-R03 from Novus Biologicals
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GGPS1 RNAi - H00009453-R02 from Novus Biologicals
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MISSION® esiRNA - EHU069361 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9261 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12755 from Sigma-Aldrich
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GGPS1 siRNA (Human) - CRH6271 from Cohesion Biosciences
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GGPS1 - MBS8224906 from MyBioSource
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shRNA set against Human GGPS1(NM_001037277.1) - SHH083333 from Creative biogene
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GGPS1 shRNA Plasmid (Human) - CHH6271 from Cohesion Biosciences
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GGPS1 miRNA 3'UTR clone - MiUTR1H-04022 from Creative biogene
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