| Gene Symbol |
COX18
|
| Entrez Gene |
285521
|
| Alt Symbol |
COX18HS
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
COX18 cytochrome c oxidase assembly factor
|
| Other Description |
cytochrome c oxidase assembly homolog 18|cytochrome c oxidase assembly protein 18|mitochondrial inner membrane protein COX18
|
| Swissprots |
Q6IPP9 Q2PB67 Q2PB66 Q49B97 Q2PB68 Q8N8Q8
|
| Accessions |
EAX05653 Q8N8Q8 AK092641 AK096310 BAC04758 AM055750 CAJ20055 AM055751 CAJ20056 AM055752 CAJ20057 AY957564 AAY35060 AY957565 AAY35061 BC071812 AAH71812 BC101684 AAI01685 BC143642 AAI43643 DA385228 DA674605 XM_005265680 XP_005265737 XM_011531878 XP_011530180 NM_001297732 NP_001284661 NM_001297733 NP_001284662 NM_001300729 NP_001287658 NM_173827 NP_776188 NM_001033760
|
| Function |
Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space. {ECO:0000269|PubMed:16911509}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:16212937}; Multi-pass membrane protein {ECO:0000269|PubMed:16212937}.
|
![Western Blot: COX18 Overexpression Lysate (Adult Normal) [NBP2-05105] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for COX18.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10344_COX18%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-05105-img0001.jpg)