Gene Symbol | COX18 |
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Entrez Gene | 285521 |
Alt Symbol | COX18HS |
Species | Human |
Gene Type | protein-coding |
Description | COX18 cytochrome c oxidase assembly factor |
Other Description | cytochrome c oxidase assembly homolog 18|cytochrome c oxidase assembly protein 18|mitochondrial inner membrane protein COX18 |
Swissprots | Q6IPP9 Q2PB67 Q2PB66 Q49B97 Q2PB68 Q8N8Q8 |
Accessions | EAX05653 Q8N8Q8 AK092641 AK096310 BAC04758 AM055750 CAJ20055 AM055751 CAJ20056 AM055752 CAJ20057 AY957564 AAY35060 AY957565 AAY35061 BC071812 AAH71812 BC101684 AAI01685 BC143642 AAI43643 DA385228 DA674605 XM_005265680 XP_005265737 XM_011531878 XP_011530180 NM_001297732 NP_001284661 NM_001297733 NP_001284662 NM_001300729 NP_001287658 NM_173827 NP_776188 NM_001033760 |
Function | Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space. {ECO:0000269|PubMed:16911509}. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:16212937}; Multi-pass membrane protein {ECO:0000269|PubMed:16212937}. |
COX18 CRISPR/Cas9 KO Plasmid (h) - sc-415427 from Santa Cruz Biotechnology
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COX18 HDR Plasmid (h) - sc-415427-HDR from Santa Cruz Biotechnology
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COX18 Double Nickase Plasmid (h) - sc-415427-NIC from Santa Cruz Biotechnology
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COX18 Double Nickase Plasmid (h2) - sc-415427-NIC-2 from Santa Cruz Biotechnology
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COX18 CRISPR Activation Plasmid (h) - sc-415427-ACT from Santa Cruz Biotechnology
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COX18 CRISPR Activation Plasmid (h2) - sc-415427-ACT-2 from Santa Cruz Biotechnology
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COX18 Lentiviral Activation Particles (h) - sc-415427-LAC from Santa Cruz Biotechnology
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COX18 Lentiviral Activation Particles (h2) - sc-415427-LAC-2 from Santa Cruz Biotechnology
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COX18 siRNA (h) - sc-89246 from Santa Cruz Biotechnology
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COX18 shRNA Plasmid (h) - sc-89246-SH from Santa Cruz Biotechnology
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COX18 shRNA (h) Lentiviral Particles - sc-89246-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU035301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6467 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6467 from Sigma-Aldrich
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COX18 siRNA (Human) - CRJ7103 from Cohesion Biosciences
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COX18 - MBS8222387 from MyBioSource
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shRNA set against Human COX18 (NM_173827.2) - SHH268209 from Creative biogene
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COX18 shRNA Plasmid (Human) - CHJ7103 from Cohesion Biosciences
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COX18 miRNA 3'UTR clone - MiUTR1H-02373 from Creative biogene
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