| Gene Symbol |
GLYATL2
|
| Entrez Gene |
219970
|
| Alt Symbol |
BXMAS2-10, GATF-B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
glycine-N-acyltransferase-like 2
|
| Other Description |
acyl-CoA:glycine N-acyltransferase-like protein 2|glycine N-acyltransferase-like protein 2|glycine acyltransferase family-B
|
| Swissprots |
Q96AT2 Q86WC3 Q8WU03 A5LGC7
|
| Accessions |
EAW73826 EAW73827 Q8WU03 AB207211 BAF63415 AF426250 AAO73139 AW264415 BC016789 AAH16789 BC021682 AAH21682 HQ447235 ADQ31722 XM_011544809 XP_011543111 NM_145016 NP_659453
|
| Function |
Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0- CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine. {ECO:0000269|PubMed:20305126}.
|
| Subcellular Location |
Endoplasmic reticulum {ECO:0000269|PubMed:20305126}.
|
| Tissue Specificity |
Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain. {ECO:0000269|PubMed:20305126}.
|