Gene Symbol | GLYATL2 |
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Entrez Gene | 219970 |
Alt Symbol | BXMAS2-10, GATF-B |
Species | Human |
Gene Type | protein-coding |
Description | glycine-N-acyltransferase-like 2 |
Other Description | acyl-CoA:glycine N-acyltransferase-like protein 2|glycine N-acyltransferase-like protein 2|glycine acyltransferase family-B |
Swissprots | Q96AT2 Q86WC3 Q8WU03 A5LGC7 |
Accessions | EAW73826 EAW73827 Q8WU03 AB207211 BAF63415 AF426250 AAO73139 AW264415 BC016789 AAH16789 BC021682 AAH21682 HQ447235 ADQ31722 XM_011544809 XP_011543111 NM_145016 NP_659453 |
Function | Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0- CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine. {ECO:0000269|PubMed:20305126}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000269|PubMed:20305126}. |
Tissue Specificity | Expressed at highest levels in salivary gland and trachea. Also detected in thyroid gland, spinal cord, prostate, lung and fetal brain. {ECO:0000269|PubMed:20305126}. |
GLYATL2 CRISPR/Cas9 KO Plasmid (h) - sc-415093 from Santa Cruz Biotechnology
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GLYATL2 HDR Plasmid (h) - sc-415093-HDR from Santa Cruz Biotechnology
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GLYATL2 Double Nickase Plasmid (h) - sc-415093-NIC from Santa Cruz Biotechnology
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GLYATL2 Double Nickase Plasmid (h2) - sc-415093-NIC-2 from Santa Cruz Biotechnology
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GLYATL2 CRISPR Activation Plasmid (h) - sc-415093-ACT from Santa Cruz Biotechnology
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GLYATL2 CRISPR Activation Plasmid (h2) - sc-415093-ACT-2 from Santa Cruz Biotechnology
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GLYATL2 Lentiviral Activation Particles (h) - sc-415093-LAC from Santa Cruz Biotechnology
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GLYATL2 Lentiviral Activation Particles (h2) - sc-415093-LAC-2 from Santa Cruz Biotechnology
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GLYATL2 siRNA (h) - sc-96946 from Santa Cruz Biotechnology
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GLYATL2 shRNA Plasmid (h) - sc-96946-SH from Santa Cruz Biotechnology
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GLYATL2 shRNA (h) Lentiviral Particles - sc-96946-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU053081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9379 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9379 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03217 from Sigma-Aldrich
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GLYATL2 siRNA (Human) - CRJ6438 from Cohesion Biosciences
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GLYATL2 - MBS8215066 from MyBioSource
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shRNA set against Human GLYATL2 (NM_145016.3) - SHH302254 from Creative biogene
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Human GLYATL2 siRNA - orb276939 from Biorbyt
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GLYATL2 shRNA Plasmid (Human) - CHJ6438 from Cohesion Biosciences
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GLYATL2 miRNA 3'UTR clone - MiUTR1H-04087 from Creative biogene
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