| Gene Symbol |
UNC119B
|
| Entrez Gene |
84747
|
| Alt Symbol |
POC7B
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
unc-119 homolog B (C. elegans)
|
| Other Description |
POC7 centriolar protein homolog B|protein unc-119 homolog B
|
| Swissprots |
A6NIH7
|
| Accessions |
A6NIH7 EAW98215 EAW98216 EAW98217 AK057021 AK126367 BAG54314 AL137327 CAH10700 BC004815 AAH04815 BC070088 DA324219 DQ893334 ABM84260 DQ896650 ABM87649 DQ896662 ABM87661 EU176802 ABW03603 EU176805 ABW03606 NM_032661 NM_001080533 NP_001074002
|
| Function |
Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells. {ECO:0000269|PubMed:22085962}.
|
| Subcellular Location |
Cell projection, cilium {ECO:0000269|PubMed:22085962}. Note=Enriched at the transition zone and extended into the proximal end of the cilium.
|