Gene Symbol | UNC119B |
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Entrez Gene | 84747 |
Alt Symbol | POC7B |
Species | Human |
Gene Type | protein-coding |
Description | unc-119 homolog B (C. elegans) |
Other Description | POC7 centriolar protein homolog B|protein unc-119 homolog B |
Swissprots | A6NIH7 |
Accessions | A6NIH7 EAW98215 EAW98216 EAW98217 AK057021 AK126367 BAG54314 AL137327 CAH10700 BC004815 AAH04815 BC070088 DA324219 DQ893334 ABM84260 DQ896650 ABM87649 DQ896662 ABM87661 EU176802 ABW03603 EU176805 ABW03606 NM_032661 NM_001080533 NP_001074002 |
Function | Myristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Binds myristoylated NPHP3 and plays a key role in localization of NPHP3 to the primary cilium membrane. Does not bind all myristoylated proteins. Probably plays a role in trafficking proteins in photoreceptor cells. {ECO:0000269|PubMed:22085962}. |
Subcellular Location | Cell projection, cilium {ECO:0000269|PubMed:22085962}. Note=Enriched at the transition zone and extended into the proximal end of the cilium. |
UNC119B CRISPR/Cas9 KO Plasmid (h) - sc-413695 from Santa Cruz Biotechnology
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UNC119B HDR Plasmid (h) - sc-413695-HDR from Santa Cruz Biotechnology
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UNC119B Double Nickase Plasmid (h) - sc-413695-NIC from Santa Cruz Biotechnology
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UNC119B Double Nickase Plasmid (h2) - sc-413695-NIC-2 from Santa Cruz Biotechnology
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UNC119B CRISPR Activation Plasmid (h) - sc-413695-ACT from Santa Cruz Biotechnology
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UNC119B CRISPR Activation Plasmid (h2) - sc-413695-ACT-2 from Santa Cruz Biotechnology
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UNC119B Lentiviral Activation Particles (h) - sc-413695-LAC from Santa Cruz Biotechnology
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UNC119B Lentiviral Activation Particles (h2) - sc-413695-LAC-2 from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU053671 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22492 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22492 from Sigma-Aldrich
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UNC119B siRNA (Human) - CRJ3608 from Cohesion Biosciences
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UNC119B - MBS8220297 from MyBioSource
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shRNA set against Human Unc119b (NM_001080533.1) - SHH440464 from Creative biogene
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Human UNC119B siRNA - orb274109 from Biorbyt
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UNC119B shRNA Plasmid (Human) - CHJ3608 from Cohesion Biosciences
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UNC119B miRNA 3'UTR clone - MiUTR1H-06288 from Creative biogene
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