| Gene Symbol |
VIPAS39
|
| Entrez Gene |
63894
|
| Alt Symbol |
C14orf133, SPE-39, SPE39, VIPAR, VPS16B, hSPE-39
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
|
| Other Description |
VPS33B-interacting protein in apical-basolateral polarity regulator|VPS33B-interacting protein in polarity and apical restriction|VPS33B-interacting protein involved in polarity and apical protein restriction|protein spe-39 homolog|spermatogenesis-defective protein 39 homolog
|
| Swissprots |
Q9H9I9 Q9H9C1 O95434 B4DPI6 Q9H7E1
|
| Accessions |
AAD09624 EAW81286 EAW81287 EAW81288 EAW81289 EAW81290 Q9H9C1 AA010625 AK022769 BAB14237 AK022925 BAB14310 AK024661 BAB14951 AK098254 BAG53601 AK222706 BAD96426 AK297388 BAG59829 AK298354 BAG60598 AW629161 BC015054 AAH15054 CR457294 CAG33575 DA794284 XM_011537066 XP_011535368 NM_001193314 NP_001180243 NM_001193315 NP_001180244 NM_001193316 NP_001180245 NM_001193317 NP_001180246 NM_022067 NP_071350
|
| Function |
May play a role in vesicular trafficking during spermatogenesis (By similarity). Plays a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes. May play a role in epithelial polarization through stabilization of apical membrane protein content, possibly via the RAB11A-dependent apical recycling pathway. Also involved in direct or indirect transcriptional regulation of E-cadherin. {ECO:0000250, ECO:0000269|PubMed:19109425, ECO:0000269|PubMed:20190753}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Early endosome. Recycling endosome. Late endosome. Note=Colocalizes in clusters with VPS33B at cytoplasmic organelles. {ECO:0000250}.
|
![Western Blot: VIPAR Overexpression Lysate (Adult Normal) [NBL1-08175] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VIPAR.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/10557_VIPAR%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08175-img0002.jpg)