HSPD1

Gene Symbol HSPD1
Entrez Gene 3329
Alt Symbol CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13
Species Human
Gene Type protein-coding
Description heat shock 60kDa protein 1 (chaperonin)
Other Description 60 kDa chaperonin|60 kDa heat shock protein, mitochondrial|P60 lymphocyte protein|chaperonin 60|heat shock protein 65|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1
Swissprots Q38L19 B2R5M6 B7Z712 Q9UCR6 P10809
Accessions AAK60260 AAX93145 AAY24018 ABB01006 CAB75426 CAO02240 EAW70148 EAW70149 EAW70150 EAW70151 EAW70152 EAW70153 P10809 AK297305 BAH12542 AK298368 BAH12768 AK298632 BAH12833 AK298844 BAH12883 AK301276 BAH13448 AK312240 BAG35173 AU098504 BC002676 AAH02676 BC003030 AAH03030 BC047350 BC067082 AAH67082 BC073746 AAH73746 BG701476 BX647145 DQ893414 ABM84340 DQ896771 ABM87770 EU719626 ACE06961 M22382 AAA60127 M34664 AAA36022 XM_005246518 XP_005246575 NM_002156 NP_002147 NM_199440 NP_955472
Function Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
Subcellular Location Mitochondrion matrix.
Top Pathways Type I diabetes mellitus, RNA degradation, Tuberculosis, Legionellosis

HSP60 (D6F1) XP ® Rabbit mAb - 12165 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D6F1
Western blot analysis of extracts from various cell lines using HSP60 (D6F1) XP ® Rabbit mAb.

HSP60 (D85) Antibody - 4869 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using HSP60 (D85) Antibody.

HSP60 (D307) Antibody - 4870 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell types using HSP60 (D307) Antibody.

HSP 60 (B-9) - sc-271215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (B-9) : sc-271215. Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic staining of glandular cells.

HSP 60 (C-10) - sc-376240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (C-10): sc-376240. Immunofluorescence staining of methanol-fixed HeLa cells showing mitochondrial localization.

HSP 60 (F-9) - sc-376261 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (F-9): sc-376261. Western blot analysis of HSP 60 expression in KNRK whole cell lysate.

HSP 60 (H-1) - sc-13115 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (H-1): sc-13115. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic staining.

HSP 60 (H-300) - sc-13966 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HSP 60 (H-300): sc-13966. Western blot analysis of HSP 60 expression in mouse placenta tissue extract (A) and HeLa whole cell lysate (B).

HSP 60 (K-19) - sc-1722 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HSP 60 (K-19): sc-1722. Immunofluorescence staining of formalin-fixed HeLa cells showing mitochondrial localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

HSP 60 (LK1) - sc-59567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (LK1): sc-59567. Immunofluorescence staining of methanol-fixed HeLa cells showing mitochondrial localization.

HSP 60 (N-20) - sc-1052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HSP 60 (N-20): sc-1052. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing cytoplasmic staining of tumor cells.

HSP 60 (SPM253) - sc-65568 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HSP 60 (SPM253): sc-65568. Western blot analysis of HSP 60 expression in 293T whole cell lysate.

HSP 60 (24) - sc-136291 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
HSP 60 (24): sc-136291. Western blot analysis of HSP 60 expression in Jurkat whole cell lysate.

HSP 60 (A57-B9) - sc-57840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

HSP 60 (A57-E4) - sc-57841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

HSP 65 (BDI577) - sc-57842 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

HSP 65 (BDI578) - sc-57843 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

HSP 65 (5178) - sc-65466 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

HSP 65 (5177) - sc-58170 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Hsp60 antibody - ab68416 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab68416 at 1µg/ml staining Hsp60 in Human mammary cancer tissue sections by Immunohistochemistry (Formalin/ PFA fixed paraffin-embedded tissue sections). The tissue sections underwent antigen retrieval by boiling. A Biotin-conjugated Goat anti-rabbit IgG was used as secondary at 1/200 dilution.

Anti-Hsp60 antibody - ab53109 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Hsp60 antibody (ab53109) at 1/300 dilutionLane 1 : extract from COLO205 cellsLane 2 : extract from COLO205 cells with immunising peptide

Anti-Hsp60 antibody - ab6530 from Abcam

Prices $387.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab6530 stained HeLa cells. The cells were 4% PFA fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab6530, 5µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-Hsp60 antibody - ab89609 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-Hsp60 antibody (ab89609) at 1 µg/ml + Human kidney lysate at 50 µgdeveloped using the ECL technique

Anti-Hsp60 antibody [1D11BD8] - Mitochondrial Marker - ab110312 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D11BD8
Anti-Hsp60 antibody [1D11BD8] - Mitochondrial Marker (ab110312) at 5 µg/ml + HepG2 whole cells at 10 µg

Anti-Hsp60 antibody [4B9/89] - ab5478 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B9/89
Immunocytochemistry/Immunofluorescence analysis of Hsp60 in A2058 Cells. Hsp60 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with ab5478 at a dilution of 1:200 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated goat anti-mouse IgG secondary antibody. Images were taken at 60X magnification.
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