Gene Symbol | HSPD1 |
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Entrez Gene | 3329 |
Alt Symbol | CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13 |
Species | Human |
Gene Type | protein-coding |
Description | heat shock 60kDa protein 1 (chaperonin) |
Other Description | 60 kDa chaperonin|60 kDa heat shock protein, mitochondrial|P60 lymphocyte protein|chaperonin 60|heat shock protein 65|mitochondrial matrix protein P1|short heat shock protein 60 Hsp60s1 |
Swissprots | Q38L19 B2R5M6 B7Z712 Q9UCR6 P10809 |
Accessions | AAK60260 AAX93145 AAY24018 ABB01006 CAB75426 CAO02240 EAW70148 EAW70149 EAW70150 EAW70151 EAW70152 EAW70153 P10809 AK297305 BAH12542 AK298368 BAH12768 AK298632 BAH12833 AK298844 BAH12883 AK301276 BAH13448 AK312240 BAG35173 AU098504 BC002676 AAH02676 BC003030 AAH03030 BC047350 BC067082 AAH67082 BC073746 AAH73746 BG701476 BX647145 DQ893414 ABM84340 DQ896771 ABM87770 EU719626 ACE06961 M22382 AAA60127 M34664 AAA36022 XM_005246518 XP_005246575 NM_002156 NP_002147 NM_199440 NP_955472 |
Function | Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Type I diabetes mellitus, RNA degradation, Tuberculosis, Legionellosis |
HSP 60 CRISPR/Cas9 KO Plasmid (h) - sc-400336 from Santa Cruz Biotechnology
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HSP 60 HDR Plasmid (h) - sc-400336-HDR from Santa Cruz Biotechnology
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HSP 60 Double Nickase Plasmid (h) - sc-400336-NIC from Santa Cruz Biotechnology
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HSP 60 Double Nickase Plasmid (h2) - sc-400336-NIC-2 from Santa Cruz Biotechnology
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HSP 60 CRISPR Activation Plasmid (h) - sc-400336-ACT from Santa Cruz Biotechnology
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HSP 60 CRISPR Activation Plasmid (h2) - sc-400336-ACT-2 from Santa Cruz Biotechnology
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HSP 60 Lentiviral Activation Particles (h) - sc-400336-LAC from Santa Cruz Biotechnology
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HSP 60 Lentiviral Activation Particles (h2) - sc-400336-LAC-2 from Santa Cruz Biotechnology
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HSP 60 siRNA (h) - sc-29351 from Santa Cruz Biotechnology
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HSP 60 shRNA Plasmid (h) - sc-29351-SH from Santa Cruz Biotechnology
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HSP 60 shRNA (h) Lentiviral Particles - sc-29351-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU113521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10382 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10382 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04500 from Sigma-Aldrich
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HSPD1 siRNA (Human) - CRH2272 from Cohesion Biosciences
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HSPD1 - MBS8218866 from MyBioSource
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HSP 60 CRISPR/Cas9 KO Plasmid (h2) - sc-400336-KO-2 from Santa Cruz Biotechnology
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HSP 60 HDR Plasmid (h2) - sc-400336-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human HSPD1(NM_002156.4) - SHH134939 from Creative biogene
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HSPD1 shRNA Plasmid (Human) - CHH2272 from Cohesion Biosciences
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HSPD1 miRNA 3'UTR clone - MiUTR1H-04746 from Creative biogene
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HSPD1 miRNA 3'UTR clone - MiUTR3H-00413 from Creative biogene
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