| Gene Symbol |
VMP1
|
| Entrez Gene |
81671
|
| Alt Symbol |
EPG3, TANGO5, TMEM49
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuole membrane protein 1
|
| Other Description |
ectopic P-granules autophagy protein 3 homolog|transmembrane protein 49|transport and golgi organization 5 homolog
|
| Swissprots |
Q96GC9 Q9H0P4 Q9P089 B4DVV9
|
| Accessions |
CAC33315 EAW94390 EAW94391 EAW94392 EAW94393 Q96GC9 AB047551 BAF47368 AF161410 AAF28970 AF214006 AAL36461 AK024969 AK025987 AK293578 BAG57048 AK293664 BAG57110 AK294854 BAG57958 AK301254 BAG62821 AL136711 CAB66646 AM393551 CAL38428 AM393627 CAL38503 AX775965 CAE11682 BC009758 AAH09758 BC024020 CR533521 CAG38552 DC428792 DQ892569 ABM83495 NM_030938 NP_112200
|
| Function |
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. {ECO:0000250, ECO:0000269|PubMed:17724469}.
|
| Subcellular Location |
Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane {ECO:0000269|PubMed:17724469}; Multi- pass membrane protein {ECO:0000269|PubMed:17724469}. Vacuole membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum {ECO:0000269|PubMed:17724469}.
|