ANK1

Gene Symbol	ANK1
Entrez Gene	286
Alt Symbol	ANK, SPH1, SPH2
Species	Human
Gene Type	protein-coding
Description	ankyrin 1, erythrocytic
Other Description	ANK-1|ankyrin-1|ankyrin-R|erythrocyte ankyrin
Swissprots	E5RFL7 Q8N604 O43400 P16157 Q13768 Q59FP2 Q53ER1 A0PJN8 A6NJ23 Q99407
Accessions	AAB46776 AAB47804 AAB47805 EAW63241 EAW63242 EAW63243 EAW63244 EAW63245 EAW63246 EAW63247 EAW63248 EAW63249 EAW63250 P16157 AA404587 AB209418 BAD92655 AI167814 AI684839 AK126647 BAG54351 AK129864 AK223578 BAD97298 BC007930 AAH07930 BC014467 BC030957 AAH30957 BC117121 AAI17122 BC156401 AAI56402 BX647936 F28948 HQ447752 ADQ32237 M28880 AAA51732 N63745 X16609 CAA34610 XM_005273476 XP_005273533 XM_011544490 XP_011542792 XM_011544491 XP_011542793 XM_011544492 XP_011542794 XM_011544493 XP_011542795 XM_011544494 XP_011542796 XM_011544495 XP_011542797 XM_011544496 XP_011542798 XM_011544497 XP_011542799 XM_011544498 XP_011542800 XM_011544499 XP_011542801 XM_011544500 XP_011542802 XM_011544501 XP_011542803 XM_011544502 XP_011542804 XM_011544503 XP_011542805 XM_011544504 XP_011542806 XM_011544505 XP_011542807 XM_011544506 XP_011542808 XR_949389 NM_000037 NP_000028 NM_001142445 NP_001135917 NM_001142446 NP_001135918 NM_020475 NP_065208 NM_020476 NP_065209 NM_020477 NP_065210 NM_020478 NP_065211 NM_020480 NP_065213 NM_020479 NM_020481
Function	Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. {ECO:0000269|PubMed:12456646}.
Subcellular Location	Isoform Mu20: Sarcoplasmic reticulum {ECO:0000305}.
Tissue Specificity	Isoform Mu17, isoform Mu18, isoform Mu19 and isoform Mu20 are expressed in skeletal muscle. Isoform Br21 is expressed in brain. {ECO:0000269|PubMed:9430667}.
Top Pathways	Proteoglycans in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ankyrin erythroid full length protein - ab157890 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

ANK1 / Ankyrin Antibody Blocking Peptide - LS-E26698 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ANK1 / Ankyrin Antibody Blocking Peptide - LS-E15333 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Ankyrin 1 Protein - H00000286-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Ankyrin 1 blocking peptide - GTX88591-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat, Bovine

Ankyrin 1 Blocking Peptide - 33R-9893 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Ankyrin 1 Blocking Peptide - 33R-6993 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Ankyrin Erythroid Peptide - AC21-1538-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Ankyrin-1 - H00000286-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Ankyrin-1 - H00000286-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ANK1 Peptide - 46-725P from ProSci Category Peptide

ANK1 fusion protein - ag11103 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ANK1 fusion protein - ag10115 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ANK1, His-tagged - ANK1-3490H from Creative Biomart Category Protein Source E. Coli or Yeast Species Human

Recombinant Ankyrin 1, Erythrocytic (ANK1) - RPB633Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human Ankyrin-1(ANK1) ,partial - CSB-YP001720HU CSB-EP001720HU CSB-BP001720HU CSB-MP001720HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Ankyrin 1, Erythrocytic Protein (Recombinant) - abx168126 from Abbexa Category Protein Source Human Species Human

Ankyrin 1, Recombinant Protein - MBS2030181 from MyBioSource Category Protein Prices $235.00, $425.00, $610.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Ankyrin-1(ANK1) ,partial, Recombinant Protein - MBS956971 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Ankyrin 1/ANK1, Peptide - MBS426113 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat, Bovine

Ankyrin 1 Recombinant Protein Antigen - NBP2-33806PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Ankyrin 1 Recombinant Protein Antigen - NBP1-90168PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SYNTHETIC Human ERYTHROCYTE ANKYRIN 2.1 Protein (OPSA10461) - OPSA10461 from Aviva Systems Biology Category Protein Prices $160.00 Sizes 50 µg Species Human

ANK1 Peptide, Human - M34GP00600H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Ankyrin 1, Erythrocytic (ANK1) - RPU52079 from Biomatik Category Protein Prices $185.00, $378.00, $578.00, $688.80 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

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