Gene Symbol |
CD226
|
Entrez Gene |
10666
|
Alt Symbol |
DNAM-1, DNAM1, PTA1, TLiSA1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
CD226 molecule
|
Other Description |
CD226 antigen|DNAX accessory molecule 1|DNAX accessory molecule-1|T lineage-specific activation antigen 1 antigen|adhesion glycoprotein|platelet and T cell activation antigen 1
|
Swissprots |
B2R818 Q15762
|
Accessions |
EAW66515 Q15762 AJ537553 CAD61184 AK313199 BAG36015 BC074787 AAH74787 DB224741 GU935335 GU935336 U56102 AAC50560 XM_005266642 XP_005266699 XM_005266643 XP_005266700 XM_006722374 XP_006722437 XM_011525792 XP_011524094 XM_011525793 XP_011524095 NM_001303618 NP_001290547 NM_001303619 NP_001290548 NM_006566 NP_006557
|
Function |
Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. {ECO:0000269|PubMed:8673704}.
|
Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
Tissue Specificity |
Expressed by peripheral blood T-lymphocytes. {ECO:0000269|PubMed:8673704}.
|
Top Pathways |
Cell adhesion molecules (CAMs)
|