Gene Symbol | CD226 |
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Entrez Gene | 10666 |
Alt Symbol | DNAM-1, DNAM1, PTA1, TLiSA1 |
Species | Human |
Gene Type | protein-coding |
Description | CD226 molecule |
Other Description | CD226 antigen|DNAX accessory molecule 1|DNAX accessory molecule-1|T lineage-specific activation antigen 1 antigen|adhesion glycoprotein|platelet and T cell activation antigen 1 |
Swissprots | B2R818 Q15762 |
Accessions | EAW66515 Q15762 AJ537553 CAD61184 AK313199 BAG36015 BC074787 AAH74787 DB224741 GU935335 GU935336 U56102 AAC50560 XM_005266642 XP_005266699 XM_005266643 XP_005266700 XM_006722374 XP_006722437 XM_011525792 XP_011524094 XM_011525793 XP_011524095 NM_001303618 NP_001290547 NM_001303619 NP_001290548 NM_006566 NP_006557 |
Function | Receptor involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. {ECO:0000269|PubMed:8673704}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Expressed by peripheral blood T-lymphocytes. {ECO:0000269|PubMed:8673704}. |
Top Pathways | Cell adhesion molecules (CAMs) |
DNAM-1 CRISPR/Cas9 KO Plasmid (h) - sc-402189 from Santa Cruz Biotechnology
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DNAM-1 HDR Plasmid (h) - sc-402189-HDR from Santa Cruz Biotechnology
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DNAM-1 Double Nickase Plasmid (h) - sc-402189-NIC from Santa Cruz Biotechnology
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DNAM-1 Double Nickase Plasmid (h2) - sc-402189-NIC-2 from Santa Cruz Biotechnology
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DNAM-1 CRISPR Activation Plasmid (h) - sc-402189-ACT from Santa Cruz Biotechnology
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DNAM-1 CRISPR Activation Plasmid (h2) - sc-402189-ACT-2 from Santa Cruz Biotechnology
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DNAM-1 Lentiviral Activation Particles (h) - sc-402189-LAC from Santa Cruz Biotechnology
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DNAM-1 Lentiviral Activation Particles (h2) - sc-402189-LAC-2 from Santa Cruz Biotechnology
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DNAM-1 siRNA (h) - sc-35202 from Santa Cruz Biotechnology
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DNAM-1 shRNA Plasmid (h) - sc-35202-SH from Santa Cruz Biotechnology
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DNAM-1 shRNA (h) Lentiviral Particles - sc-35202-V from Santa Cruz Biotechnology
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DNAM-1/CD226 RNAi - H00010666-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN5701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5701 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09443 from Sigma-Aldrich
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CD226 siRNA (Human) - CRH7273 from Cohesion Biosciences
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CD226 - MBS8213363 from MyBioSource
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shRNA set against Human CD226 (NM_006566.2) - SHH258753 from Creative biogene
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CD226 shRNA Plasmid (Human) - CHH7273 from Cohesion Biosciences
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CD226 miRNA 3'UTR clone - MiUTR4H-TG01874 from Creative biogene
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