| Gene Symbol |
DUSP18
|
| Entrez Gene |
150290
|
| Alt Symbol |
DSP18, DUSP20, LMWDSP20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dual specificity phosphatase 18
|
| Other Description |
dual specificity protein phosphatase 18|low molecular weight dual specificity phosphatase 20
|
| Swissprots |
B3KPA4 Q8NEJ0
|
| Accessions |
EAW59913 EAW59914 EAW59915 Q8NEJ0 AF461689 AAN77931 AF533017 AAN59787 AI699242 AK025036 AK056074 BAG51616 BC004110 BC028724 BC030987 AAH30987 BM550612 CR456406 CAG30292 CU012964 CAK54395 CU013252 CAK54694 DA378760 XM_005261368 XP_005261425 XM_006724148 XP_006724211 XM_011529920 XP_011528222 XM_011529921 XP_011528223 NM_001304794 NP_001291723 NM_001304795 NP_001291724 NM_001304796 NP_001291725 NM_152511 NP_689724
|
| Function |
Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. In vitro, dephosphorylates p-nitrophenyl phosphate (pNPP).
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12408986}. Nucleus {ECO:0000269|PubMed:12408986}.
|
| Tissue Specificity |
Widely expressed with highest levels in liver, brain, ovary and testis. {ECO:0000269|PubMed:12408986, ECO:0000269|PubMed:12591617}.
|