Gene Symbol |
ATG10
|
Entrez Gene |
83734
|
Alt Symbol |
APG10, APG10L, pp12616
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
autophagy related 10
|
Other Description |
ATG10 autophagy related 10 homolog|autophagy-related protein 10|ubiquitin-like-conjugating enzyme ATG10
|
Swissprots |
Q9H0Y0 Q9H842 Q6PIX1 B2RE09
|
Accessions |
EAW95881 EAW95882 EAW95883 EAW95884 EAW95885 EAW95886 Q9H0Y0 AF318326 AAL55833 AI436652 AK024016 BAB14778 AK225969 AK315752 BAG38106 AL136912 CAB66846 AM393858 CAL38733 BC004551 BC027718 BC029268 AAH29268 DQ892432 ABM83358 DQ895644 ABM86570 XM_005248610 XP_005248667 XM_005248611 XP_005248668 XM_005248612 XP_005248669 XM_011543660 XP_011541962 XM_011543661 XP_011541963 NM_001131028 NP_001124500 NM_031482 NP_113670
|
Function |
E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. {ECO:0000250, ECO:0000269|PubMed:21367888}.
|
Subcellular Location |
Cytoplasm {ECO:0000305}.
|
Top Pathways |
Regulation of autophagy
|