Gene Symbol | ATG10 |
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Entrez Gene | 83734 |
Alt Symbol | APG10, APG10L, pp12616 |
Species | Human |
Gene Type | protein-coding |
Description | autophagy related 10 |
Other Description | ATG10 autophagy related 10 homolog|autophagy-related protein 10|ubiquitin-like-conjugating enzyme ATG10 |
Swissprots | Q9H0Y0 Q9H842 Q6PIX1 B2RE09 |
Accessions | EAW95881 EAW95882 EAW95883 EAW95884 EAW95885 EAW95886 Q9H0Y0 AF318326 AAL55833 AI436652 AK024016 BAB14778 AK225969 AK315752 BAG38106 AL136912 CAB66846 AM393858 CAL38733 BC004551 BC027718 BC029268 AAH29268 DQ892432 ABM83358 DQ895644 ABM86570 XM_005248610 XP_005248667 XM_005248611 XP_005248668 XM_005248612 XP_005248669 XM_011543660 XP_011541962 XM_011543661 XP_011541963 NM_001131028 NP_001124500 NM_031482 NP_113670 |
Function | E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3 (By similarity). Plays a role in adenovirus-mediated cell lysis. {ECO:0000250, ECO:0000269|PubMed:21367888}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Top Pathways | Regulation of autophagy |
Atg10 CRISPR/Cas9 KO Plasmid (h) - sc-405748 from Santa Cruz Biotechnology
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Atg10 HDR Plasmid (h) - sc-405748-HDR from Santa Cruz Biotechnology
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Atg10 Double Nickase Plasmid (h) - sc-405748-NIC from Santa Cruz Biotechnology
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Atg10 Double Nickase Plasmid (h2) - sc-405748-NIC-2 from Santa Cruz Biotechnology
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Atg10 CRISPR Activation Plasmid (h) - sc-405748-ACT from Santa Cruz Biotechnology
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Atg10 CRISPR Activation Plasmid (h2) - sc-405748-ACT-2 from Santa Cruz Biotechnology
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Atg10 Lentiviral Activation Particles (h) - sc-405748-LAC from Santa Cruz Biotechnology
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Atg10 Lentiviral Activation Particles (h2) - sc-405748-LAC-2 from Santa Cruz Biotechnology
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Atg10 siRNA (h) - sc-72576 from Santa Cruz Biotechnology
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Atg10 shRNA Plasmid (h) - sc-72576-SH from Santa Cruz Biotechnology
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Atg10 shRNA (h) Lentiviral Particles - sc-72576-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN3642 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3642 from Sigma-Aldrich
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ATG10 siRNA (Human) - CRJ3182 from Cohesion Biosciences
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ATG10 - MBS8238286 from MyBioSource
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shRNA set against Human ATG10 (NM_031482.4) - SHH242014 from Creative biogene
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Human ATG10 siRNA - orb273683 from Biorbyt
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ATG10 shRNA Plasmid (Human) - CHJ3182 from Cohesion Biosciences
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ATG10 miRNA 3'UTR clone - MiUTR3H-11473 from Creative biogene
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ATG10 miRNA 3'UTR clone - MiUTR3H-11474 from Creative biogene
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