PDLIM5

Gene Symbol PDLIM5
Entrez Gene 10611
Alt Symbol ENH, ENH1, L9, LIM
Species Human
Gene Type protein-coding
Description PDZ and LIM domain 5
Other Description PDZ and LIM domain protein 5|enigma homolog|enigma-like LIM domain protein|enigma-like PDZ and LIM domains protein
Swissprots Q8WVK0 Q5UW38 Q56VN4 D6RB78 Q96HC4 O60705 A8K6F9 E9PBF5
Accessions AAY40898 EAX06053 EAX06054 EAX06055 EAX06056 EAX06057 EAX06058 EAX06059 Q96HC4 AA253314 AA614664 AA888262 AA922628 AB209531 BAD92768 AF061258 AAC15767 AF116705 AAF71125 AI201986 AK027217 AK129886 AK291624 BAF84313 AK291898 BAF84587 AK296980 BAH12467 AK304125 BAH14111 AL049969 AL832157 AL832686 AL833151 AL833438 AL833439 AM393306 CAL38184 AM393394 CAL38272 AM393485 CAL38362 AM393621 CAL38497 AM393813 CAL38688 AY345240 AAR09142 AY598328 AAT06739 BC008741 AAH08741 BC017902 AAH17902 BC026029 BF954250 BF979604 BM670741 BP260089 BQ049008 BT007328 AAP35992 D31139 DA381128 DA895978 DQ890686 ABM81612 DQ893868 ABM84794 XM_005262693 XP_005262750 XM_005262695 XP_005262752 XM_005262696 XP_005262753 XM_005262698 XP_005262755 XM_006714066 XP_006714129 XM_006714067 XP_006714130 XM_006714068 XP_006714131 XM_006714069 XP_006714132 XM_006714070 XP_006714133 XM_011531543 XP_011529845 NM_001011513 NP_001011513 NM_001011515 NP_001011515 NM_001011516 NP_001011516 NM_001256425 NP_001243354 NM_001256426 NP_001243355 NM_001256427 NP_001243356 NM_001256428 NP_001243357 NM_001256429 NP_001243358 NM_006457 NP_006448 NR_046186
Function May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Detected both at presynaptic and postsynaptic sites. {ECO:0000250}.
Tissue Specificity Heart and skeletal muscle specific. Expression is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression. {ECO:0000269|PubMed:10429367, ECO:0000269|PubMed:16044170, ECO:0000269|PubMed:16213469}.

PDLIM5 (Q-18) - sc-82014 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PDLIM5 (P-18) - sc-82013 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PDLIM5 (P-18): sc-82013. Western blot analysis of PDLIM5 expression in K-562 whole cell lysate.

PDLIM5 (JK-3R) - sc-81813 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PDLIM5 (JK-3R): sc-81813. Western blot analysis of PDLIM5 expression in A-431 whole cell lysate.

PDLIM5 (E-25) - sc-133900 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
PDLIM5 (E-25): sc-133900. Western blot analysis of PDLIM5 expression in Hep G2 whole cell lysate.

Anti-PDLIM5 (phospho Y251) antibody - ab138402 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PDLIM5 (phospho Y251) antibody (ab138402) at 1/500 dilution + K562 cell extracts at 30 µg

Anti-PDLIM5 antibody - ab196559 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Human SOD full length protein (ab159559) at 1/500 dilutionLane 1 : HL60 extractsLane 2 : BT474 extractsLane 3 : HepG2 extractsLane 4 : MCF7 extractsLane 5 : Mouse lung extractsLane 6 : Mouse heart extractsLane 7 : Mouse kidney extractsLane 8 : Mouse uterus extracts

Anti-PDLIM5 antibody - ab135274 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PDLIM5 antibody (ab135274) at 1/500 dilution + Extracts from A549 cells at 30 µg

Anti-PDLIM5 antibody - ab56723 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-PDLIM5 / LIM Antibody - LS-C334242 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U20S cell using PDLIM5 antibody. Blue: DAPI for nuclear staining.

Anti-PDLIM5 / LIM Antibody (aa546-596) IHC-plus™ - LS-B11243 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-PDLIM5 / LIM antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11243 dilution 1:100.

Anti-PDLIM5 / LIM Antibody (N-Terminus) - LS-C16212 from LifeSpan Bioscience

Prices $495.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDLIM5 / LIM Antibody (aa1-597) - LS-C37195 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-PDLIM5 / LIM Antibody (C-Terminus) - LS-C31310 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-PDLIM5 / LIM Antibody (aa165-214) - LS-C30549 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-PDLIM5 / LIM Antibody (N-Terminus) - LS-C101709 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDLIM5 antibody LS-C101709 Western blot of HepG2 cell lysate.

Anti-PDLIM5 / LIM Antibody (aa108-157) - LS-C109889 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PDLIM5 antibody LS-C109889 Western blot of HepG2 cell lysate.

Anti-PDLIM5 / LIM Antibody (clone 1C11) - LS-C173642 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C11
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM5.

Anti-PDLIM5 / LIM Antibody (phospho-Tyr251) - LS-C291515 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PDLIM5 / LIM Antibody (aa375-425) - LS-C288491 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PDLIM5 / LIM Antibody (aa1-597, Azide-free) - LS-C328175 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PDLIM5 / LIM Antibody (Ser257) - LS-C177408 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PDLIM5 (S257) pAb in extracts from A549 cells.

Anti-PDLIM5 / LIM Antibody (phospho-Tyr251) - LS-C178062 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of p-CD318 (Y707) pAb in extracts from K562 cells.

Anti-PDLIM5 / LIM Antibody (aa208-257) - LS-C199963 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of PDLIM5 antibody in extracts from A549 cells.

Anti-PDLIM5 / LIM Antibody (clone 1B5) - LS-C173815 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B5
Western blot of extracts (35 ug) from 9 different cell lines by using anti-${SYMBOL} monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Anti-PDLIM5 / LIM Antibody (clone 1H10) - LS-C173816 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H10
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDLIM5 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDLIM5.
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