| Gene Symbol |
Lias
|
| Entrez Gene |
305348
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
lipoic acid synthetase
|
| Other Description |
LS {ECO:0000255|HAMAP-Rule:MF_03123}|lip-syn {ECO:0000255|HAMAP-Rule:MF_03123}|lipoate synthase {ECO:0000255|HAMAP-Rule:MF_03123}|lipoic acid synthase {ECO:0000255|HAMAP-Rule:MF_03123}|lipoyl synthase, mitochondrial|lipoyl synthase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03123}
|
| Swissprots |
Q5XIH4
|
| Accessions |
CBN72402 Q5XIH4 BC083708 AAH83708 XM_008770155 XP_008768377 XM_008770156 XP_008768378 NM_001012037 NP_001012037
|
| Function |
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
|
| Subcellular Location |
Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
|
| Top Pathways |
Lipoic acid metabolism
|