Gene Symbol |
VGF
|
Entrez Gene |
7425
|
Alt Symbol |
SCG7, SgVII
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
VGF nerve growth factor inducible
|
Other Description |
neuro-endocrine specific protein VGF|neurosecretory protein VGF
|
Swissprots |
O15240 Q9UDW8
|
Accessions |
AAD45830 CAA73210 CBX47485 EAW50201 O15240 AK225839 BC006217 BC036537 BC044212 AAH44212 BC063835 AAH63835 XM_005250561 XP_005250618 XM_011516548 XP_011514850 XM_011516549 XP_011514851 NM_003378 NP_003369
|
Function |
Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris.
|
Subcellular Location |
Secreted {ECO:0000269|PubMed:19194657}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:19194657}. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus.
|
Tissue Specificity |
Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells. {ECO:0000269|PubMed:19194657}.
|