Gene Symbol | VGF |
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Entrez Gene | 7425 |
Alt Symbol | SCG7, SgVII |
Species | Human |
Gene Type | protein-coding |
Description | VGF nerve growth factor inducible |
Other Description | neuro-endocrine specific protein VGF|neurosecretory protein VGF |
Swissprots | O15240 Q9UDW8 |
Accessions | AAD45830 CAA73210 CBX47485 EAW50201 O15240 AK225839 BC006217 BC036537 BC044212 AAH44212 BC063835 AAH63835 XM_005250561 XP_005250618 XM_011516548 XP_011514850 XM_011516549 XP_011514851 NM_003378 NP_003369 |
Function | Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris. |
Subcellular Location | Secreted {ECO:0000269|PubMed:19194657}. Cytoplasmic vesicle, secretory vesicle {ECO:0000269|PubMed:19194657}. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus. |
Tissue Specificity | Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells. {ECO:0000269|PubMed:19194657}. |
VGF CRISPR/Cas9 KO Plasmid (h) - sc-402030 from Santa Cruz Biotechnology
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VGF HDR Plasmid (h) - sc-402030-HDR from Santa Cruz Biotechnology
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VGF Double Nickase Plasmid (h) - sc-402030-NIC from Santa Cruz Biotechnology
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VGF Double Nickase Plasmid (h2) - sc-402030-NIC-2 from Santa Cruz Biotechnology
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VGF CRISPR Activation Plasmid (h) - sc-402030-ACT from Santa Cruz Biotechnology
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VGF CRISPR Activation Plasmid (h2) - sc-402030-ACT-2 from Santa Cruz Biotechnology
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VGF Lentiviral Activation Particles (h) - sc-402030-LAC from Santa Cruz Biotechnology
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VGF Lentiviral Activation Particles (h2) - sc-402030-LAC-2 from Santa Cruz Biotechnology
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VGF siRNA (h) - sc-42328 from Santa Cruz Biotechnology
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VGF shRNA Plasmid (h) - sc-42328-SH from Santa Cruz Biotechnology
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VGF shRNA (h) Lentiviral Particles - sc-42328-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22675 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22675 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04891 from Sigma-Aldrich
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VGF siRNA (Human) - CRH5081 from Cohesion Biosciences
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VGF - MBS8217450 from MyBioSource
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shRNA set against Human VGF (NM_003378.3) - SHH442656 from Creative biogene
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Human VGF siRNA - orb265583 from Biorbyt
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VGF shRNA Plasmid (Human) - CHH5081 from Cohesion Biosciences
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VGF miRNA 3'UTR clone - MiUTR4H-TG12755 from Creative biogene
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