USP33

Gene Symbol	USP33
Entrez Gene	23032
Alt Symbol	VDU1
Species	Human
Gene Type	protein-coding
Description	ubiquitin specific peptidase 33
Other Description	VHL-interacting deubiquitinating enzyme 1|deubiquitinating enzyme 33|pVHL-interacting deubiquitinating enzyme 1|ubiquitin carboxyl-terminal hydrolase 33|ubiquitin thioesterase 33|ubiquitin thiolesterase 33|ubiquitin-specific-processing protease 33
Swissprots	Q9H9F0 Q9UPQ5 Q96AV6 Q8TEY7 Q8TEY6
Accessions	EAX06367 EAX06368 EAX06369 EAX06370 EAX06371 Q8TEY7 AB029020 BAA83049 AF383172 AAL78314 AF383173 AAL78315 AI569971 AK022864 BAB14279 AK023664 AK094056 AK225499 AK308402 AL050140 CAB43288 BC016663 AAH16663 BU631866 DB232523 DQ891487 ABM82413 DQ894672 ABM85598 XM_005270648 XP_005270705 XM_005270649 XP_005270706 XM_011541055 XP_011539357 XM_011541056 XP_011539358 XR_946588 XR_946589 NM_015017 NP_055832 NM_201624 NP_963918 NM_201626 NP_963920
Function	Deubiquitinating enzyme involved in various processes such as centrosome duplication, cellular migration and beta-2 adrenergic receptor/ADRB2 recycling. Involved in regulation of centrosome duplication by mediating deubiquitination of CCP110 in S and G2/M phase, leading to stabilize CCP110 during the period which centrioles duplicate and elongate. Involved in cell migration via its interaction with intracellular domain of ROBO1, leading to regulate the Slit signaling. Plays a role in commissural axon guidance cross the ventral midline of the neural tube in a Slit-dependent manner, possibly by mediating the deubiquitination of ROBO1. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of beta-arrestins (ARRB1 and ARRB2) and beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting ly
Subcellular Location	Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes predominantly in S and G2 phases but less in G1 phase.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:11739384}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human USP33 protein fragment - ab127357 from Abcam Category Protein Source E. coli Species Human

USP33 / VDU1 Antibody Blocking Peptide - LS-E29556 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

USP33 / VDU1 Antibody Blocking Peptide - LS-E29558 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

USP33 / VDU1 Antibody Blocking Peptide - LS-E6910 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human USP33 Protein - H00023032-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

USP33 Recombinant Protein - H00023032-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

USP33 Peptide - P0980 from Novus Biologicals Category Peptide Species Human

VDU1-Antibody-C-term-Blocking-peptide - BP2166b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP33 / VDU1 - H00023032-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

USP33 / VDU1 - H00023032-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

USP33 / VDU1 - H00023032-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

USP33 fusion protein - Ag2695 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

USP33 fusion protein - Ag14268 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human USP33, GST-tagged - USP33-3627H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human USP3, His-SUMO-tagged - USP33-154H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human Ubiquitin carboxyl-terminal hydrolase 33(USP33) ,partial - CSB-YP840583HU CSB-EP840583HU CSB-BP840583HU CSB-MP840583HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

USP33 / VDU1 (transcript variant 2) - TP317069 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

USP33 Recombinant Protein Antigen - NBP1-82931PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

VDU1-I-Antibody-C-term-Blocking-Peptide - BP2167b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VDU1-Antibody-N-term-Blocking-peptide - BP2166a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

VDU1-I-Antibody-N-term-Blocking-Peptide - BP2167a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

USP33 Peptide, Human - M34GP17176H from Creative Peptides Category Peptide Source Synthetic. Species Human

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