Gene Symbol | Lepr |
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Entrez Gene | 16847 |
Alt Symbol | LEPROT, Leprb, Modb1, OB-RGRP, Obr, db, diabetes, obese-like, obl |
Species | Mouse |
Gene Type | protein-coding |
Description | leptin receptor |
Other Description | B219|LEP-R|OB receptor|leptin receptor gene-related protein |
Swissprots | Q64309 Q61215 O54986 P48356 Q9QWV5 O35686 Q9QWG3 |
Accessions | AAB95332 AAB95333 AAB95334 AAB95335 AAD13218 AAD41084 EDL30863 EDL30864 EDL30865 EDL30866 P48356 AB519174 BAI47482 AB519175 BAI47483 AB519176 BAI47484 AB519177 BAI47485 AB519178 BAI47486 AK136231 AK140785 BAE24478 AK143989 BAE25649 AK155891 BC082551 AAH82551 CJ319649 CN692760 U42467 AAA93014 U46135 AAC52408 U49106 AAC52420 U49107 AAC52421 U49108 AAC52422 U49109 AAC52423 U49110 AAC52424 U52915 AAC52599 U58861 AAC52705 U58862 AAC52706 U58863 AAC52707 Y10296 CAA71342 Y10298 CAA71343 NM_001122899 NP_001116371 NM_010704 NP_034834 NM_146146 NP_666258 |
Function | Isoform E could function as a transport protein. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Isoform A: highest level of expression in lung and kidney, also present in kidney, heart, brain, spleen, liver, muscle, choroid plexus and hypothalamus. Isoform B: highest level of expression in hypothalamus and lower level in brain, testes and adipose tissue. Isoform E: expressed in adipose tissue, hypothalamus, heart, and testes. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Ob-R (I-17) - sc-33982 from Santa Cruz Biotechnology
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Ob-R (K-20) - sc-1835 from Santa Cruz Biotechnology
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Ob-R (S-18) - sc-33981 from Santa Cruz Biotechnology
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p-Ob-R (Tyr 1138) - sc-16421 from Santa Cruz Biotechnology
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Anti-Leptin Receptor antibody - ab43406 from Abcam
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Anti-Leptin Receptor antibody - ab7211 from Abcam
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Anti-Leptin Receptor antibody - ab7212 from Abcam
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Anti-Leptin Receptor antibody [RM0085-9C29] - ab86060 from Abcam
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Anti-H-2Kb/Db Antibody (clone 28-8-6) - LS-C47976 from LifeSpan Bioscience
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Leptin R Antibody (RM0085-9C29) - NBP1-21725 from Novus Biologicals
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Anti-Leptin Receptor antibody produced in goat - L9536 from Sigma-Aldrich
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Leptin Receptor antibody - GTX27211 from GeneTex
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Leptin Receptor antibody - GTX27212 from GeneTex
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Leptin Receptor antibody - GTX130069 from GeneTex
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Leptin Receptor antibody [9C29] - GTX53174 from GeneTex
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Anti -LEPR (Leptin Receptor) - 216784 from USBiological Life Science
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Anti -Leptin Receptor (LEPR, LEP-R, B219, CD295, Db, Leprb, LEPROT, Modb1, MGC105189,Obese Receptor, OB Receptor, OBR, OB-R, Obese-like, Obl, OB-RGRP) - L1671-03R from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-09 from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-09A from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-10 from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-10A from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-11 from USBiological Life Science
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Anti -Leptin Receptor (OBR, LEPR, B219, Obese Receptor) - L1671-11A from USBiological Life Science
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CD295 / Leptin Receptor antibody - DM3586P from Acris Antibodies
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Rabbit Anti-Leptin Receptor Antibody - 168-11002 from RayBiotech
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