Gene Symbol | Lepr |
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Entrez Gene | 16847 |
Alt Symbol | LEPROT, Leprb, Modb1, OB-RGRP, Obr, db, diabetes, obese-like, obl |
Species | Mouse |
Gene Type | protein-coding |
Description | leptin receptor |
Other Description | B219|LEP-R|OB receptor|leptin receptor gene-related protein |
Swissprots | Q64309 Q61215 O54986 P48356 Q9QWV5 O35686 Q9QWG3 |
Accessions | AAB95332 AAB95333 AAB95334 AAB95335 AAD13218 AAD41084 EDL30863 EDL30864 EDL30865 EDL30866 P48356 AB519174 BAI47482 AB519175 BAI47483 AB519176 BAI47484 AB519177 BAI47485 AB519178 BAI47486 AK136231 AK140785 BAE24478 AK143989 BAE25649 AK155891 BC082551 AAH82551 CJ319649 CN692760 U42467 AAA93014 U46135 AAC52408 U49106 AAC52420 U49107 AAC52421 U49108 AAC52422 U49109 AAC52423 U49110 AAC52424 U52915 AAC52599 U58861 AAC52705 U58862 AAC52706 U58863 AAC52707 Y10296 CAA71342 Y10298 CAA71343 NM_001122899 NP_001116371 NM_010704 NP_034834 NM_146146 NP_666258 |
Function | Isoform E could function as a transport protein. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Isoform A: highest level of expression in lung and kidney, also present in kidney, heart, brain, spleen, liver, muscle, choroid plexus and hypothalamus. Isoform B: highest level of expression in hypothalamus and lower level in brain, testes and adipose tissue. Isoform E: expressed in adipose tissue, hypothalamus, heart, and testes. |
Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Adipocytokine signaling pathway, Non-alcoholic fatty liver disease (NAFLD), AMPK signaling pathway |
Recombinant Mouse Leptin R Fc Chimera, CF - 7814-LR-050 from R&D Systems
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Recombinant Mouse Lepr, His-tagged - Lepr-01M from Creative Biomart
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Recombinant Mouse Leptin Receptor - Lepr-1766M from Creative Biomart
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Recombinant Leptin Receptor (LEPR) - RPA083Hu01 from Uscn Life Science Inc.
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Recombinant Leptin Receptor (LEPR) - RPA083Mu01 from Uscn Life Science Inc.
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Recombinant Leptin Receptor (LEPR) - RPA083Mu02 from Uscn Life Science Inc.
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Recombinant Leptin Receptor (LEPR) - RPA083Ra01 from Uscn Life Science Inc.
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Recombinant Leptin Receptor (LEPR) - RPA083Po01 from Uscn Life Science Inc.
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Recombinant Leptin Receptor (LEPR) - RPA083Mu01 from Cloud-clone
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Recombinant Leptin Receptor (LEPR) - RPA083Mu02 from Cloud-clone
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Recombinant Mouse Leptin receptor(Lepr) ,partial - CSB-YP012871MO CSB-EP012871MO CSB-BP012871MO CSB-MP012871MO from Cusabio
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Recombinant Mouse Leptin R Fc Chimera Protein - 497-LR from R&D Systems
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Recombinant Mouse Leptin R Fc Chimera Protein, CF - 497-LR/CF from R&D Systems
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Recombinant Mouse Leptin R Fc Chimera Protein, CF - 7814-LR from R&D Systems
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Leptin Receptor Protein (Recombinant) - abx167219 from Abbexa
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Recombinant Mouse LEPR Protein - LEPR-9049M from Creative Biomart
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Recombinant Leptin Receptor (LEPR) - RPU51467 from Biomatik
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LEPR Recombinant Protein (OPCD04917) - OPCD04917 from Aviva Systems Biology
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Leptin receptor (Lepr), partial, Recombinant Protein - MBS958913 from MyBioSource
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