C8A

Gene Symbol	C8A
Entrez Gene	731
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	complement component 8, alpha polypeptide
Other Description	complement component 8 subunit alpha|complement component C8 alpha chain
Swissprots	Q13668 A2RUI4 P07357 A2RUI5 Q9H130
Accessions	AAA82124 EAX06644 EAX06645 EAX06646 P07357 AK309596 BC020702 AAH20702 BC132911 AAI32912 BC132913 AAI32914 HQ258328 ADR83082 M16974 AAA52200 XM_011542079 XP_011540381 NM_000562 NP_000553
Function	Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. {ECO:0000269|PubMed:17872444, ECO:0000269|PubMed:7440581}.
Subcellular Location	Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C8A overexpression lysate - LY424641 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

C8A 293 Cell Lysate - 410195 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

Complement C8A Overexpression Lysate (Native) - NBP2-09010 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

C8A Over-expression Lysate Product - GWB-5AD920 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Human Complement C8 Deficient Plasma (EDTA) - D810104 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (EDTA) - D810105 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (EDTA) - D810106 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Heparin) - D810107 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Heparin) - D810108 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Heparin) - D810109 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Sodium Citrate) - D810101 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Sodium Citrate) - D810102 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Plasma

Human Complement C8 Deficient Plasma (Sodium Citrate) - D810103 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Plasma

Human Complement C8 Deficient Serum - D810110 from AssayPro Category Blood Product Prices $40.00 Sizes 1 ml Species Human Tissue Serum

Human Complement C8 Deficient Serum - D810111 from AssayPro Category Blood Product Prices $200.00 Sizes 10 ml Species Human Tissue Serum

Human Complement C8 Deficient Serum - D810112 from AssayPro Category Blood Product Prices $1,600.00 Sizes 100 ml (10 vials x 10 ml) Species Human Tissue Serum

Panoply™ Human C8A Knockdown Stable Cell Line - CSC-DC002160 from Creative biogene Category Cell Line Species Human

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