C8A

Gene Symbol	C8A
Entrez Gene	731
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	complement component 8, alpha polypeptide
Other Description	complement component 8 subunit alpha|complement component C8 alpha chain
Swissprots	Q13668 A2RUI4 P07357 A2RUI5 Q9H130
Accessions	AAA82124 EAX06644 EAX06645 EAX06646 P07357 AK309596 BC020702 AAH20702 BC132911 AAI32912 BC132913 AAI32914 HQ258328 ADR83082 M16974 AAA52200 XM_011542079 XP_011540381 NM_000562 NP_000553
Function	Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C8A inserts into the target membrane, but does not form pores by itself. {ECO:0000269|PubMed:17872444, ECO:0000269|PubMed:7440581}.
Subcellular Location	Secreted. Cell membrane; Multi-pass membrane protein. Note=Secreted as soluble protein. Inserts into the cell membrane of target cells.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Complement C8 full length protein - ab167812 from Abcam Category Protein Source Native Species Human

C8A fusion protein - ag18056 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

C8A fusion protein - Ag18389 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Complement component C8 alpha chain(C8A) - CSB-YP004194HU CSB-EP004194HU CSB-BP004194HU CSB-MP004194HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Complement Component 8a (C8a) - RPD784Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Complement Component 8a (C8a) - RPD784Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

C8A Peptide, Human - M34GP02160H from Creative Peptides Category Peptide Source Synthetic. Species Human

Complement component C8 alpha chain (C8A), Recombinant Protein - MBS962239 from MyBioSource Category Protein Prices $1,350.00, $1,350.00, $1,570.00, $1,570.00, $2,240.00, $2,240.00, $2,700.00, $2,700.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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