| Gene Symbol |
TXN2
|
| Entrez Gene |
25828
|
| Alt Symbol |
MT-TRX, MTRX, TRX2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin 2
|
| Other Description |
mitochondrial thioredoxin|thioredoxin, mitochondrial|thioredoxin-2
|
| Swissprots |
Q5JZA0 Q9UH29 Q6FH60 Q99757
|
| Accessions |
EAW60103 EAW60104 Q99757 AF276920 AAF86467 AF480262 AAN05576 AK123361 AK130187 AK301837 BAG63281 BC013726 AAH13726 BC050610 AAH50610 CR456601 CAG30487 CR541896 CAG46694 CR541917 CAG46715 CU013201 CAK54632 CU013489 CAK54931 DQ891579 ABM82505 DQ894772 ABM85698 DQ895044 ABM85970 U78678 AAB41631 XM_005261508 XP_005261565 XM_006724226 XP_006724289 XM_011530111 XP_011528413 NM_012473 NP_036605
|
| Function |
Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity. {ECO:0000269|PubMed:12032145, ECO:0000269|PubMed:12080052}.
|
| Subcellular Location |
Mitochondrion {ECO:0000269|PubMed:12032145, ECO:0000269|PubMed:12080052}.
|
| Tissue Specificity |
Widely expressed in adult (at protein level) and fetal tissues. {ECO:0000269|PubMed:12032145, ECO:0000269|PubMed:12080052}.
|
