| Gene Symbol |
HS3ST6
|
| Entrez Gene |
64711
|
| Alt Symbol |
3-OST-6, HS3ST5, h3-OST-6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
|
| Other Description |
heparan sulfate (glucosamine) 3-O-sulfotransferase 5|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 6|heparan sulfate glucosamine 3-O-sulfotransferase 6|heparan sulphate D-glucosaminyl 3-O-sulfotransferase-3B like
|
| Swissprots |
Q96QI5 Q96RX7
|
| Accessions |
AAK61299 EAW85602 EAW85603 Q96QI5 BC156438 AAI56439 BC172540 AAI72540 CK300523 DY654407 XM_011522608 XP_011520910 XM_011522609 XP_011520911 XM_011546749 XP_011545051 XM_011546750 XP_011545052 NM_001009606 NP_001009606
|
| Function |
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3- OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. {ECO:0000269|PubMed:15303968}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|