| Gene Symbol |
C19orf80
|
| Entrez Gene |
55908
|
| Alt Symbol |
ANGPTL8, PRO1185, PVPA599, RIFL, TD26
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chromosome 19 open reading frame 80
|
| Other Description |
angiopoietin-like protein 8|betatrophin variant 1|betatrophin variant 2|hepatocellular carcinoma-associated gene TD26|hepatocellular carcinoma-associated protein TD26|lipasin|refeeding-induced fat and liver protein
|
| Swissprots |
Q9NQZ1 Q6UXH0
|
| Accessions |
EAW84185 EAW84186 Q6UXH0 AF271350 AAF76204 AY358356 AAQ88722 BC113823 AAI13824 BC141563 AAI41564 BC146552 AAI46553 BF511595 BP316755 KF809856 AHH82583 KF809857 AHH82584 KF809858 AHH82585 NM_018687 NP_061157
|
| Function |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (By similarity). {ECO:0000250|UniProtKB:Q8R1L8, ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577}.
|
| Subcellular Location |
Secreted {ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:23623304}.
|
| Tissue Specificity |
Predominantly expressed in liver. Also expressed in adipose tissues. {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:23623304}.
|