Gene Symbol | C19orf80 |
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Entrez Gene | 55908 |
Alt Symbol | ANGPTL8, PRO1185, PVPA599, RIFL, TD26 |
Species | Human |
Gene Type | protein-coding |
Description | chromosome 19 open reading frame 80 |
Other Description | angiopoietin-like protein 8|betatrophin variant 1|betatrophin variant 2|hepatocellular carcinoma-associated gene TD26|hepatocellular carcinoma-associated protein TD26|lipasin|refeeding-induced fat and liver protein |
Swissprots | Q9NQZ1 Q6UXH0 |
Accessions | EAW84185 EAW84186 Q6UXH0 AF271350 AAF76204 AY358356 AAQ88722 BC113823 AAI13824 BC141563 AAI41564 BC146552 AAI46553 BF511595 BP316755 KF809856 AHH82583 KF809857 AHH82584 KF809858 AHH82585 NM_018687 NP_061157 |
Function | Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (By similarity). {ECO:0000250|UniProtKB:Q8R1L8, ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:23623304}. |
Tissue Specificity | Predominantly expressed in liver. Also expressed in adipose tissues. {ECO:0000269|PubMed:22569073, ECO:0000269|PubMed:22809513, ECO:0000269|PubMed:23150577, ECO:0000269|PubMed:23623304}. |
LOC55908 CRISPR/Cas9 KO Plasmid (h) - sc-412637 from Santa Cruz Biotechnology
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LOC55908 HDR Plasmid (h) - sc-412637-HDR from Santa Cruz Biotechnology
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LOC55908 Double Nickase Plasmid (h) - sc-412637-NIC from Santa Cruz Biotechnology
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LOC55908 Double Nickase Plasmid (h2) - sc-412637-NIC-2 from Santa Cruz Biotechnology
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LOC55908 CRISPR Activation Plasmid (h) - sc-412637-ACT from Santa Cruz Biotechnology
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LOC55908 CRISPR Activation Plasmid (h2) - sc-412637-ACT-2 from Santa Cruz Biotechnology
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LOC55908 Lentiviral Activation Particles (h) - sc-412637-LAC from Santa Cruz Biotechnology
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LOC55908 Lentiviral Activation Particles (h2) - sc-412637-LAC-2 from Santa Cruz Biotechnology
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LOC55908 siRNA (h) - sc-97856 from Santa Cruz Biotechnology
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LOC55908 shRNA Plasmid (h) - sc-97856-SH from Santa Cruz Biotechnology
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LOC55908 shRNA (h) Lentiviral Particles - sc-97856-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12420 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12420 from Sigma-Aldrich
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C19orf80 siRNA (Human) - CRJ1007 from Cohesion Biosciences
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C19orf80 - MBS8220225 from MyBioSource
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Human C19orf80 siRNA - orb271508 from Biorbyt
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C19orf80 shRNA Plasmid (Human) - CHJ1007 from Cohesion Biosciences
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