| Gene Symbol |
NDUFA8
|
| Entrez Gene |
4702
|
| Alt Symbol |
CI-19KD, CI-PGIV, PGIV
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
|
| Other Description |
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8|NADH-ubiquinone oxidoreductase 19 kDa subunit|NADH:ubiquinone oxidoreductase PGIV subunit|complex I PGIV subunit|complex I-19kD|complex I-PGIV
|
| Swissprots |
Q9Y6N0 P51970 B1AM93
|
| Accessions |
EAW87511 P51970 AF044953 AAD42056 AK301520 BAH13504 AK314135 BAG36825 BC001016 AAH01016 BU602971 XM_005251998 XP_005252055 NM_014222 NP_055037
|
| Function |
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:21310150}; Peripheral membrane protein {ECO:0000269|PubMed:21310150}. Mitochondrion intermembrane space {ECO:0000269|PubMed:21310150}.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|