Gene Symbol | NDUFA8 |
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Entrez Gene | 4702 |
Alt Symbol | CI-19KD, CI-PGIV, PGIV |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa |
Other Description | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8|NADH-ubiquinone oxidoreductase 19 kDa subunit|NADH:ubiquinone oxidoreductase PGIV subunit|complex I PGIV subunit|complex I-19kD|complex I-PGIV |
Swissprots | Q9Y6N0 P51970 B1AM93 |
Accessions | EAW87511 P51970 AF044953 AAD42056 AK301520 BAH13504 AK314135 BAG36825 BC001016 AAH01016 BU602971 XM_005251998 XP_005252055 NM_014222 NP_055037 |
Function | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:21310150}; Peripheral membrane protein {ECO:0000269|PubMed:21310150}. Mitochondrion intermembrane space {ECO:0000269|PubMed:21310150}. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFA8 CRISPR/Cas9 KO Plasmid (h) - sc-408755 from Santa Cruz Biotechnology
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NDUFA8 HDR Plasmid (h) - sc-408755-HDR from Santa Cruz Biotechnology
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NDUFA8 Double Nickase Plasmid (h) - sc-408755-NIC from Santa Cruz Biotechnology
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NDUFA8 Double Nickase Plasmid (h2) - sc-408755-NIC-2 from Santa Cruz Biotechnology
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NDUFA8 CRISPR Activation Plasmid (h) - sc-408755-ACT from Santa Cruz Biotechnology
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NDUFA8 CRISPR Activation Plasmid (h2) - sc-408755-ACT-2 from Santa Cruz Biotechnology
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NDUFA8 Lentiviral Activation Particles (h) - sc-408755-LAC from Santa Cruz Biotechnology
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NDUFA8 Lentiviral Activation Particles (h2) - sc-408755-LAC-2 from Santa Cruz Biotechnology
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NDUFA8 siRNA (h) - sc-92963 from Santa Cruz Biotechnology
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NDUFA8 shRNA Plasmid (h) - sc-92963-SH from Santa Cruz Biotechnology
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NDUFA8 shRNA (h) Lentiviral Particles - sc-92963-V from Santa Cruz Biotechnology
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NDUFA8 RNAi - H00004702-R01 from Novus Biologicals
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MISSION® esiRNA - EHU050041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15146 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15146 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00314 from Sigma-Aldrich
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NDUFA8 siRNA (Human) - CRH3116 from Cohesion Biosciences
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shRNA set against Human NDUFA8 (NM_014222.2) - SHH350600 from Creative biogene
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shRNA set against Human NDUFA8(NM_014222.2) - SHR004848 from Creative biogene
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NDUFA8 shRNA Plasmid (Human) - CHH3116 from Cohesion Biosciences
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NDUFA8 miRNA 3'UTR clone - MiUTR1H-06699 from Creative biogene
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