| Gene Symbol | Glud1 |
|---|---|
| Entrez Gene | 24399 |
| Alt Symbol | Ac2-281, Gdh1, Glud, Gludeha, MRG-2 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | glutamate dehydrogenase 1 |
| Other Description | glutamate dehydrogenase 1, mitochondrial|memory-related gene 2 protein |
| Swissprots | P10860 Q6LC16 Q66HI8 |
| Accessions | CAA45717 EDL88881 EDL88882 P10860 AY321350 AAP86282 BC081841 AAH81841 FQ210745 FQ212113 FQ212750 FQ214067 FQ219417 U95148 AAB70012 X14044 CAA32202 X14223 CAA32441 NM_012570 NP_036702 |
| Function | Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle (By similarity). May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. {ECO:0000250, ECO:0000269|PubMed:9275181}. |
| Subcellular Location | Mitochondrion matrix. |
| Tissue Specificity | Widely expressed throughout the hippocampus. After induction by training, highly expressed in the dentate gyrus, pyrimidal layer and lacunosum molecolare. {ECO:0000269|PubMed:9275181}. |
| Top Pathways | Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, D-Glutamine and D-glutamate metabolism |
Recombinant Rat Glutamate dehydrogenase 1, mitochondrial(Glud1) - CSB-YP009544RA CSB-EP009544RA CSB-BP009544RA CSB-MP009544RA from Cusabio
|
||||||||||
Recombinant Rat GLUD1 Protein - GLUD1-2579R from Creative Biomart
|
||||||||||
Glutamate dehydrogenase 1, mitochondrial (Glud1), Recombinant Protein - MBS718369 from MyBioSource
|
||||||||||