HFE

Gene Symbol	HFE
Entrez Gene	3077
Alt Symbol	HFE1, HH, HLA-H, MVCD7, TFQTL2
Species	Human
Gene Type	protein-coding
Description	hemochromatosis
Other Description	MHC class I-like protein HFE|hereditary hemochromatosis protein|hereditary hemochromatosis protein HLA-H|high Fe
Swissprots	Q9HC83 Q96KU7 O75929 B2CKL0 Q96KU6 Q17RT0 Q96KU5 Q9HC70 Q9HC68 Q30201 Q9HC64 O75931 Q96KU8 O75930
Accessions	AAB82083 AAD00449 AAF01222 AAK16502 AAM82608 AAM91950 ACB21042 AEB15974 AEX30801 AEX30802 AEX30803 AEX30804 AEX30805 AEX30806 AEX30807 AEX30808 AEX30809 AEX38002 AEX38003 AEX91880 AEX91881 AEX91882 AEX91883 AEX91884 AEX91885 AEY71945 AEY71947 AEY71948 AEY71949 AEY71950 AEY71951 AFI39663 AFI39664 AFI39665 AFI39666 AFI39667 AFI39668 AFI39669 AFI39670 AFI39671 AFI39672 AFI39673 AFI39674 AFI39675 AFI39676 AFI39677 AFI39678 AFI39679 AFI39680 AFI39681 AFI39682 AFI39683 AFI39685 AFI39686 AFP66572 AFU50508 AFU50509 AFU50510 AFU50511 AFU50512 AIS82617 AIS82618 AIS82619 AIS82620 AIS82621 AIS82622 AIS82623 AIS82624 AIS82625 AIS82626 AIS82627 AIS82628 AIS82629 AIS82630 AIS82631 AIS82632 AIS82633 CAA70934 CAB07442 CAJ42862 EAW55516 EAW55517 EAW55518 EAW55519 EAW55520 EAW55521 EAW55522 EAW55523 EAW55524 EAW55525 EAW55526 EAW55527 Q30201 AF079407 AAC62646 AF079408 AAC62647 AF079409 AAC62648 AF109385 AAD52104 AF115264 AAG29571 AF115265 AAG29572 AF144240 AAG29575 AF144242 AAG29577 AF147392 AF149804 AAG29342 AJ249335 CAC67792 AJ249336 CAC67793 AJ249337 CAC67794 AJ249338 CAC67795 AJ250635 CAC80805 AJ298839 AJ298840 AJ404378 AK293393 BAG56902 AK300933 BAG62562 AK316502 BAH14873 AY205604 AAO47091 BC074721 AAH74721 BC117201 AAI17202 BC117203 AAI17204 BC143887 HQ258197 ADR82951 JN375752 AEO50365 JN375753 AEO50366 JN375754 AEO50367 JN375755 AEO50368 JN375756 AEO50369 JN375757 AEO50370 JN375758 AEO50371 JN375759 AEO50372 U60319 AAC51823 XM_011514543 XP_011512845 XM_011514544 XP_011512846 XR_241893 NM_000410 NP_000401 NM_001300749 NP_001287678 NM_139003 NP_620572 NM_139004 NP_620573 NM_139006 NP_620575 NM_139007 NP_620576 NM_139008 NP_620577 NM_139009 NP_620578 NM_139010 NP_620579 NM_139011 NP_620580 NM_139002 NM_139005
Function	Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. {ECO:0000269|PubMed:9465039}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed in all tissues tested except brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HFE peptide - ab87815 from Abcam Category Peptide

Human HFE protein fragment - ab139241 from Abcam Category Protein Source E. coli Species Human

HFE Antibody Blocking Peptide - LS-E16265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HFE Antibody Blocking Peptide - LS-E16266 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

HFE Antibody Blocking Peptide - LS-E8274 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human HFE Protein - H00003077-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human HFE Protein - NBP2-23110 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

HFE-Antibody-Center-Blocking-Peptide - BP6544c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

HFE-Antibody-N-term-Blocking-Peptide - BP6544a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human HFE protein - orb191060 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source E. coli Species Human

HFE Blocking Peptide - 33R-6012 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HFE Blocking Peptide - 33R-2879 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

HFE protein (His tag) - 30R-2933 from Fitzgerald Category Protein Prices $295.00 Sizes 100 µg Source E.coli

HFE / HLAH (23-306, His-tag) - AR50693PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

HFE / HLAH (23-306, His-tag) - AR50693PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

HFE / HLAH - H00003077-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

HFE / HLAH - H00003077-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

HFE, 23-306aa, Human, His tag, E.coli - 01-P1869 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

HFE fusion protein - ag12448 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

HFE fusion protein - ag12461 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Human HFE Recombinant Protein - GWB-PPAT31 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 100 μg, 500 μg Source E.coli Species Human

Recombinant Human HFE, His-tagged - HFE-7087H from Creative Biomart Category Protein Source E. coli Species Human

HLA-H (I104) Peptide - BS3876P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Hereditary hemochromatosis protein(HFE) - CSB-YP653744HU CSB-EP653744HU CSB-BP653744HU CSB-MP653744HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

HFE, 23-306aa, Human, His tag, E.coli (Denatured) - ATGP1869 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 20 µg, 100 µg, 500 µg Species Human

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